Therapeutic observation on acupuncture-moxibustion at different intervals forpersistent allergic rhinitis

不同频次针灸治疗持续性变应性鼻炎的疗效观察

Objective:To observe the therapeutic effect of acupuncture-moxibustion at different intervals on persistent allergic rhinitis.Methods:A total of 90 patie nts con forming to the inclusi on criteria were ran domized into three groups n amed A,B and C by randomized block method.Patients in all tMee groups received the same treatment of acupuncture and herbal cake-partitioned moxibustion at the same acupoints,while the treatment frequency was different.Patients in group A received the treatment once a week,group B twice a week and group C three times a week,and all the treatment lasted for 4 weeks.The total nasal symptom score(TNSS),total ocular symptom score(TOSS)and Sino-nasal outcome test-20(SNOT-20)were evaluated before and after treatment.The self-rating score of symptoms was evaluated during treatment and 2 weeks after treatment.Results:The total effective rate was 80.0%in group A,93.3%in group B,and 100.0%in group C.The total effective rate in group A was statistically different from that in group B and group C(both P<0.05),but there was no significant inter-group difference in total effective rate between group B and group C(P>0.05).After treatment,scores of TNSS,TOSS and SNOT-20 in all three groups dropped significantly,and stat:istically different from those before treatment(all P<0.05);between-group comparison showed group B and group C decreased more obvious than group A(all P<0.05).In self-rating score of symptoms,there were no inter-group statistically significant differences in the first 3-week treatment(all P>0.05);after 4-week treatment,the score in group A was higher than that in group B and group C,and showed statistical significant(both P<0.05);at 2 weeks after treatment,the score in group A was higher than that in group B and group C based on an everyday record,showing statistical significanee(both P<0.05).At the 11th day after treatment,the score in group B was higher than that in group C(P<0.05).There were no significant differences between group B and group C at other time points(all P>0.05).Conclusion:All three protocols are effective for allergic rhin itis.With the in crease of treatme nt freque ncy,the therapeutic efficacy with a treatment frequency of twice a week and three times a week is superior to that of once a week.Frequency of three times a week has a better long-term effect than once and twice a week,together with the least fluctuation of symptoms.

目的:观察不同频次针灸治疗持续性变应性鼻炎的临床疗效。方法:将符合纳入标准的90例患者,采用随机区组法分为A组、B组和C组。三组治疗方法相同,均采用相同穴位进行针刺和隔药饼灸,但三组治疗频次不同,A组每周治疗1次,B组每周治疗2次,C组每周治疗3次。三组均治疗4周。观察三组治疗后鼻部症状总评分(TNSS)、眼部症状总评分(TOSS)和鼻腔鼻窦结局评分(SNOT-20)的变化。观察治疗期间及治疗结束后2周患者症状自主评分变化。结果:A组总有效率80.0%,B组总有效率93.3%,C组总有效率100.0%;A组总有效率与B、C组的差异均有统计学意义(均P<0.05),B组和C组总有效率无统计学差异(P>0.05)oTNSS,TOSS和SNOT-20评分方面,治疗后,三组评分均较同组治疗前陥低,组内差异右统计学意义(均P<0.05);组间比较,B、C两组评分较A组降低更明显(均P<0.05)。症状自主评分方面,治疗前3周三组评分无统计学差异(均P>0.05);第4周时A组评分高于B组和C组,组间差异有统计学意义(均P<0.05);治疗结束后2周A组每天的评分均高于B组和C组,组间差异有统计学意义(均PV0.05);治疗结亲后第11天B组高于C组(PV0.05),其余时间B组和C组差异无统计学意义(均P>0.05)o结论:三种治疗频次对于持续性变应性鼻炎患者均有效,且随着治疗时间的累计,每周2次及每周3次治疗的疗效优于每周1次。每周3次较每周1次及每周2次更能维持疗效,且治疗结束后患者症状波动最小。