期刊文献+

基于化疗药物的药效特性论治恶性肿瘤 被引量:9

Treatment of Malignant Tumors Based on Pharmacodynamic Characteristics of Chemotherapeutic Drugs
下载PDF
导出
摘要 据WHO年报资料显示:在全球看来,当今恶性肿瘤的发病率及死亡率表现为一种逐渐上升的趋势,甚至对发展中国家而言,其癌谱表现出与发达国家常见肿瘤并存的现象,其中对大多数恶性肿瘤而言,化疗药物成为了中晚期及术后的辅助疗法。结合临床观察,正如中医的"热者寒之、寒者热之"等理论,可猜测化疗药物的寒热与肿瘤的阴阳之性之间存在关联趋同性,这种特性有助于促进肿瘤的治疗疗效。根据"察色按脉,先别阴阳"的中医辨证,结合西医中肿瘤的好发部位、病理类型等辨别肿瘤的寒热之性,然后针对性地分析化疗药物的寒热属性,将化疗药物的寒热及肿瘤的温凉之性相结合,从而对肿瘤有更好的"穿透力"、"破坏力",甚至对淋巴及远处转移达到一种更好的抑制作用。 1.According to the WHO annual report,the incidence and mortality of malignant tumors are on the rise globally.Even for developing countries,their cancer spectrum shows the coexistence of common tumors in developed countries.For most malignant tumors,chemotherapeutic drugs have become adjuvant therapies in advanced and post-operative stages.2.Combining with clinical observation,just like the theory of“heat is cold,cold is heat”of traditional Chinese medicine,we can speculate that there is a relationship between the cold and heat of chemotherapy drugs and the Yin-Yang nature of tumors,which is helpful to promote the therapeutic effect of tumors.3.According to the traditional Chinese medicine dialectics of “observing color according to pulse,distinguishing Yin and Yang first”,distinguishing the cold and heat of tumors according to the location and pathological type of tumors in western medicine,then analyzing the cold and heat attributes of chemotherapeutic drugs,combining the cold and heat of chemotherapeutic drugs with the warmth and cooling of tumors,so as to have better u penetrating power",destructive power"to tumors,and even to lymph nodes and distant metastasis.To achieve a better inhibition.
作者 田雲 杜晓泉 肖尧 TIAN Yun;DU Xiaoquan;XIAO Yao(Shaanxi University of Traditional Chinese Medicine,Xianyang Sharmxi 71200,China;The First Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang Shaanxi 112046,China;The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Cheng Du Sichuan 610074,China)
出处 《四川中医》 2020年第2期42-45,共4页 Journal of Sichuan of Traditional Chinese Medicine
基金 陕西省中医药管理局(编号:15-SCJH005)
关键词 恶性肿瘤 化疗药物 寒热温凉 Malignant tumors Chemotherapeutic grugs Drug characteristics
  • 相关文献

参考文献4

二级参考文献58

  • 1贾玫,李忠.恶性淋巴瘤的中西医结合诊治[J].中国临床医生杂志,2007,35(5):24-27. 被引量:9
  • 2Piva R,Chiarle R,Manazza AD,et al.Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas.Blood,2006,107:689-697.
  • 3Seidemann K,Tiemann M,Schrappe M,et al.Short-pulse B-non-Hodgkin lymphoma-type chemotherapy is efficacious treatment for pediatric anaplastie large cell lymphoma:a report of the Berlin-Frankfurt-Munster Group Trial NHL-BFM 90.Blood,2001,97:3699-3706.
  • 4Li CC,Tien HF,Tang JL,et al.Treatment outcome and pattern of failure in 77 patients with sinonasal natural killer/T-cell or T-cell lymphoma.Cancer,2004,100:366-375.
  • 5Hermine O,Allard I,Levy V,et al.A prospective phase Ⅱ clinical trial with the use of zidovudine and interferonalpha in the acute and lymphoma forms of adult T-cell leukemia/lymphoma.Hematol J,2002,3:276-282.
  • 6Besson C,Panelatti G,Delaunay C,et al.Treatment of adult T-cell leukemia-lymphoma by CHOP followed by therapy with antinucleosides,alpha interferon and oral etoposide.Leuk Lymphoma,2002,43:2275-2279.
  • 7Nasr R,El-Sabban ME,Karam.JA,et al.Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-Ⅰ associated adult T-cell leukemia/lymphoma.Oncogene,2005,24:419-430.
  • 8Rodriguez J,Munsell M,Yazji S,et al.Impact of high-dose chemotherapy on peripheral T-cell lymphomas.J Clin Oncol,2001,19:3766-3770.
  • 9Blystad AK,Enblad G,Kvaloy S,et al.High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas.Bone Marrow Transplant,2001,27:711-716.
  • 10Song KW,Mollee P,Keating A,et al.Autologous stem cell transplant for relapsed and refractory peripheral T-cell lymphoma:variable outcome according to pathological subtype.Br J Haematol,2003,120:978-985.

共引文献8

同被引文献186

引证文献9

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部