健脾治法防治肝癌的研究进展

Research Progress on Prevention and Treatment of Liver Cancer by Invigorating Spleen

综述近年来健脾治法防治肝癌的临床及实验概况,发现健脾治法在肝癌治疗过程中发挥着积极的作用,与其他治法结合能够明显改善患者生存质量、延长生存期。实验研究也证实健脾类的方药能够调控肝癌微环境,抑制肝癌细胞增殖,诱导肝癌细胞凋亡,抑制肝癌的发生发展。这为今后临床抗癌新法和新药的研制,及健脾类方药进一步的开发应用提供了新的思路。

This paper summarizes the clinical and experimental overview of liver cancer prevention and treatment under the guidance of Invigorating spleen in recent years. Invigorating spleen is an important therapeutic principle in the clinical prevention and treatment of hepatocellular carcinoma in TCM. At present, it is commonly used in combination with other therapies, which improves the therapeutic effect of patients with hepatocellular carcinoma and plays a positive role in the prognosis of patients after operation. Animal and cell experiments show that spleen-invigorating prescriptions can effectively improve the micro-environment of hepatocellular carcinoma, inhibit the occurrence of tumors, inhibit the proliferation of cancer cells and induce apoptosis.It shows that the Invigorating spleen has definite curative effect in the prevention and treatment of liver cancer,and provides a reference for clinical differentiation, treatment and scientific research of liver cancer.