右美托咪定在肩袖损伤修复术后的镇痛效果研究

Study on Analgesic Effect of Dexmedetomidine in Patients with Rotator Cuff Repair

【目的】探讨右美托咪定在肩袖损伤修复手术后的镇痛效果。【方法】本院收治的关节镜下肩袖修复术患者41例,依据随机数表法将患者分为观察组21例和对照组20例,两组患者均给于烽脉全身麻醉,观察组给予右美托咪定镇痛,对照组给于等量的生理盐水。比较两组患者一般情况、术后2 h、4 h、8h、12h、24h镇静、镇痛评分及不良反应发生情况。【结果】观察组患者术后2h、4h、8h的视觉模拟评分(VAS评分)明显低于对照组,且两组相比较差异均有显箸性(P<0.05);观察组患者术后2h、4h镇静Ramsay评分明显高于对照组,且差异均有显著性(P<0.05)。观察组总不良反应发生率为23.81(5/21),与对照组的20.0%(4/20)相比较差异无显著性(P>0.05).【结论】右美托咪定可有效延长肩袖损伤修复手术患者的术后首次镇痛时间,减轻患者的疼痛。

【Objective】To explore the analgesic effect of dexmedetomidine(Dex)in patients with rotator cuff repair surgery.【Methods】A total of 41 cases of shoulder arthroscopic rotator cuff repair in our hospital were selected.According to the random number table method,the patients were randomly divided into the observation group(21 cases)and the control group(20 cases).All patients were given intravenous general anesthesia.While the observation group also received Dex and the control group received an equal amount of physiological saline.The general data,sedation and analgesia scores at 2,4,8,12 and 24 hours after operation were compared between the two groups.The incidence of adverse reactions in the two groups was compared as well.【Results】The visual analogue scale(VAS)scores of the observation group were lower than those of the control group at 2h,4h and 8h after operation(P<0.05).The sedation Ramsay scores at 2h and 4h after surgery were higher than those of the control group.The differences were statistically significant(P<0.05).The overall incidence of adverse reactions in the observation group was 23.81%(5/21),which was no statistical significance(P>0.05)compared to 20%(4/20)in the control group.【Conclusion】Dexmedetomidine can effectively prolong the first postoperative analgesia time in patients with rotator cuff repair surgery and reduce the pain of patients.