摘要
银屑病是一种免疫介导的慢性炎症性皮肤病,其发病与基因、免疫、环境等因素密切相关。传统的与银屑病相关的共病主要包括心血管疾病、肥胖和炎症性肠病等,越来越多的研究发现其他一些疾病与银屑病之间的密切关联,包括代谢综合征、慢性肾脏疾病、肿瘤、感染等。本文总结现有研究报道的银屑病相关共病,分析这些疾病与银屑病可能的共同发病机制。
Psoriasis is an immune-mediated chronic inflammatory disease,whose occurrence is closely associated with genes,immunity,environment and other factors.Classic comorbidities associated with psoriasis mainly include cardiovascular diseases,obesity and inflammatory bowel diseases.Emerging data have shown some other diseases closely associated with psoriasis,including metabolic syndrome,chronic renal diseases,tumors,infections,and so on.This review summarizes psoriasis-associated comorbidities that have been reported in studies,and analyzes the possible co-pathogenesis of these diseases and psoriasis.
作者
陈文娟
彭琛
丁杨峰
史玉玲
Chen Wenjuan;Peng Chen;Ding Yangfeng;Shi Yuling(Institute of Psoriasis,Tongji University School of Medicine,Department of Dermatology,Shanghai Skin Disease Hospital,Shanghai 200443,China;Institute of Psoriasis,Tongji University School of medicine,Department of Dermatology and Venereology,Tenth People's Hospital of Tongji Universityt Shanghai 200072,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2020年第2期147-151,共5页
Chinese Journal of Dermatology
基金
国家自然科学基金(81872522、81673050)
上海市科委科研计划项目(18140901800)
上海市教委科研创新计划项目(2019-01-07-00-07-E00046)
上海市卫生系统优秀人才培养计划项目(2018BR30)
上海申康医院发展中心临床科技创新项目(SHDC12018X06)。
关键词
银屑病
共病现象
心血管疾病
糖尿病
肥胖症
代谢疾病
自身免疫疾病
Psoriasis
Comorbidity
Cardiovascular diseases
Diabetes mellitus
Obesity
Metabolic diseases
Autoimmune diseases
