营养毒理学研究进展与展望

Progress and prospect of nutritional toxicology

营养毒理学是营养学与毒理学交叉融合形成的一门新学科,主要研究营养素过量对人体的不良作用及其可耐受最高摄入量的制定、营养素对毒物毒性及其代谢过程的影响、膳食来源的有毒有害物质对营养素代谢和营养过程的影响以及营养素/食物(成分)的风险-收益评估等,并在此基础上提出相应的预防控制措施。经过30多年的发展,营养毒理学的学科体系不断完善,在保障食品安全,促进人类健康方面将发挥越来越大的作用。

Nutritional toxicology is a new discipline formed by the cross-integration of science of nutrition and toxicology, which mainly investigates the following aspects: adverse effects of excessive nutrients on human body and establishment of tolerable upper intake levels for nutrients, effects of nutrients against toxic effects and toxicokinetics of toxicants, effects of dietary-source toxic substances on nutrients and their metabolism and nutrient processes, risk-benefit assessment of nutrients/food(components), and on these basis, proposing corresponding preventive and control measures. After more than 30 years of development, discipline system of nutritional toxicology has improved gradually, and it will play a more important role in safeguarding food safety and promoting human health.