2015年中国十五省老年居民电视时间与血脂水平的关联

Correlation between TV time and blood lipid level of elderly residents in 15 provinces of China in 2015

[背景]老年居民是血脂异常高发和以静坐为主要生活方式的群体。静坐行为与血脂异常相关。但中国目前关于老年居民静坐时间和血脂水平状况的研究还很不足。[目的]了解我国老年居民不同电视时间水平组的血脂含量及血脂异常患病率的关系,为静坐时间与血脂异常关系研究提供科学依据。[方法]研究资料来源于2015年"中国居民营养状况变迁的队列研究",选择十五省(直辖市、自治区)(后简称:十五省)的60岁及以上的老年居民作为研究对象,通过问卷收集受访者过去一年平均每周的电视时间、身体活动量,并测量其血清总胆固醇(TC)、血清甘油三酯(TG)、血清低密度脂蛋白胆固醇(LDL-C)、血清高密度脂蛋白胆固醇(HDL-C)等指标。按照三分位法将电视时间分为低、中、高三水平。参照《中国成人血脂异常防治指南》(2016年)判定各项血脂异常情况。采用线性回归分析连续性变量在不同电视时间水平的总变化趋势。采用卡方趋势检验分析分类变量在不同电视时间水平的总变化趋势。采用多因素线性回归分析不同电视时间水平与血脂含量的关系。采用多因素logistic回归分析不同电视时间水平下血脂异常的患病风险。[结果]调查对象共4301人,其中男性占47.2%。男性低、中、高水平电视时间组分为<14、14~21、>21 h/周;女性分为<10.5、10.5~17.5、>17.5 h/周。男性的TC含量、TG含量、LDL-C含量、高LDL-C血症患病率均随电视时间水平增加而呈升高趋势;HDL-C含量随电视时间水平增加呈下降趋势。女性的TG含量、低HDL-C血症患病率均随电视时间水平增加呈升高趋势。在调整了混杂因素(年龄、城乡、学历、收入、吸烟、饮酒、身体活动量、膳食、体重指数、腰加了围0).0后84,、多0.因05素7 g线/L性,回女归性显高示水男平性电中视水时平间电组视的T时G间含组量的比TC低、水LD平L-C组含增量加比了低0.1水38平g/组L分;别多增因素logistic回归显示男性高TC血症在中水平、高水平电视时间组的患病风险是低水平组的1.7(95%CI:1.2~2.5)、1.6(95%CI:1.1~2.4)倍;男性高LDL-C血症在中水平、高水平电视时间组的患病风险是低水平组的1.6(95%CI:1.1~2.3)、1.5(95%CI:1.0~2.1)倍。女性低HDL-C血症在高水平电视时间组的患病风险是低水平组的1.4(95%CI:1.1~1.8)倍。[结论]中国十五省老年居民电视时间与男性的TC、LDL-C和女性的TG含量均呈正相关,且增加男性高TC血症、高LDL-C血症的患病风险,增加女性低HDL-C血症的患病风险。

[Background]Elderly residents have a high incidence of dyslipidemia and feature sedentary lifestyles.Sedentary behavior is associated with dyslipidemia.However,studies on sedentary time and blood lipid level of elderly residents in China are still insufficient.[Objective]This study investigates the correlation between blood lipid level and dyslipidemia prevalence of elderly residents with different lengths of TV time in China,and to provide a scientific basis for the study on the relationship between sedentary behavior and dyslipidemia.[Methods]Data were derived from the China Nutritional Transition Cohort Study 2015,where elderly residents aged 60 years and above in 15 provinces(including municipalities and autonomous regions)(hereinafter referred to as 15 provinces)of China were selected as study subjects and were asked to complete a questionnaire on their average weekly TV time and physical activity in the past year,as well as biochemical measurements such as total cholesterol(TC),triglyceride(TG),low-density lipoprotein-cholestrol(LDL-C),and highdensity lipoprotein-cholestrol(HDL-C).TV time was tertiled into low,middle,and high levels.Dyslipidemia was determined according to the Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults(2016).Linear regression was used to analyze the trend of continuous variables across different TV time levels.Chi-square trend test was used to analyze the trend of classified variables in different TV time levels.Multiple linear regression was used to analyze the effects of different TV time levels on blood lipid levels.Multiple logistic regression was used to analyze the risk of dyslipidemia at different TV time levels.[Results]A total of 4301 elderly residents were surveyed,of which 47.2%were men.The groups of low,middle,and high levels of TV time were divided into<14,14-21,and>21 h/week for males,and<10.5,10.5-17.5,and>17.5 h/week for females.The contents of TC,TG,and LDL-C and the prevalence of high LDL-C level all increased with higher TV time levels,and the content of HDL-C decreased with higher TV time levels for males.The TG content and the prevalence of low HDL-C level increased with higher TV time levels for females.After adjusting for confounding factors(age,residence,educational background,income,smoking,drinking,physical activity level,diet,body mass index,and waist circumference),the multiple linear regression results showed that the TC and LDL-C levels in the middle-level TV time male group increased by 0.084 and 0.057 g/L respectively compared with those in the low-level group,while the TG level in the high-level TV time female group increased by 0.138 g/L compared with that in the low-level group.The multiple logistic regression results showed that the risks of hypercholesterolemia in the middle-and high-level TV time groups for males were 1.7(95%CI:1.2-2.5)and 1.6(95%CI:1.1-2.4)times higher than that in the low-level group respectively;the risks of high LDL-C level in the middle-and high-level TV time groups for males were 1.6(95%CI:1.1-2.3)and 1.5(95%CI:1.0-2.1)times higher than that in the low-level group respectively;the risk of low HDL-C level in the high-level TV time group for females was 1.4(95%CI:1.1-1.8)times higher than that in the low-level group.[Conclusion]The TV time of elderly residents in 15 provinces of China has positive correlations with the TC and LDL-C levels for men and with the TG level for women,and is associated with increased risks of hypercholesterolemia and high LDL-C level for men and low HDL-C level for women.