青壮年脑卒中的独立危险因素分析

Analysis on independent risk factors for stroke in young adults

目的分析影响青壮年脑卒中的独立危险因素。方法选取2016年1月~2018年1月在辽宁省人民医院治疗的60例青壮年脑卒中患者作为脑卒中组。选取同期在辽宁省人民医院进行健康体检的60例青壮年作为健康组。比较脑卒中组和健康组在性别、饮酒、长效避孕药使用频率、椎动脉夹层、卵圆孔未闭等方面是否存在差异,采用Logistic回归分析影响青壮年脑卒中的独立危险因素。结果脑卒中组的饮酒≥30 g/d、高血压、糖尿病、长效避孕药使用频率≥3次/年、椎动脉夹层、卵圆孔未闭占比均高于健康组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,饮酒≥30 g/d(β=0.227,OR=1.255,95%CI=1.129~1.395)、高血压(β=0.139,OR=1.149,95%CI=1.069~1.236)、糖尿病(β=0.284,OR=1.328,95%CI=1.200~1.471)、长效避孕药使用频率≥3次/年(β=0.276,OR=1.318,95%CI=1.223~1.420)、椎动脉夹层(β=0.262,OR=1.300,95%CI=1.211~1.395)、卵圆孔未闭(β=0.271,OR=1.311,95%CI=1.215~1.415)是影响青壮年脑卒中的危险因素(P<0.05)。结论饮酒、高血压、糖尿病、长效避孕药使用频率、椎动脉夹层、卵圆孔未闭是影响青壮年脑卒中的危险因素。

Objective To analyze the independent risk factors influencing stroke in young adults.Methods A total of 60 young adult patients with stroke who were treated in Liaoning Provincial People′s Hospital during the period from January 2016 to January 2018 were enrolled in stroke group.A total of 60 healthy young adults who underwent physical examination in the same period in Liaoning Provincial People′s Hospital were enrolled as healthy group.The differences in gender,drinking,diabetes mellitus,long-acting contraceptives,vertebral artery dissection and patent foramen ovale(PFO)were compared between stroke group and healthy group.Logistic regression equation was performed to analyze the independent risk factors influencing stroke in young adults.Results The proportions of patients with drinking not less than 30 g/d,hypertension,frequency of long-acting contraceptives not less than 3 times/year,vertebral artery dissection and PFO in stroke group were higher than those in healthy group,the differences were statistically significant(P<0.05).Logistic regression analysis showed that amount of alcohol not less than 30 g/d(β=0.227,OR=1.255,95%CI=1.129-1.395),hypertension(β=0.139,OR=1.149,95%CI=1.069-1.236),diabetes mellitus(β=0.284,OR=1.328,95%CI=1.200-1.471),use frequency of long-acting contraceptives not less than 3 times/year(β=0.276,OR=1.318,95%CI=1.223-1.420),vertebral artery dissection(β=0.262,OR=1.300,95%CI=1.211-1.395)and PFO(β=0.271,OR=1.311,95%CI=1.215-1.415)were all independent risk factors influencing stroke in young adults(P<0.05).Conclusion Drinking,hypertension,diabetes mellitus,use frequency of long-acting contraceptives,vertebral artery dissection and PFO are all risk factors influencing stroke in young adults.