化瘀消汤合中药外敷治疗异位妊娠的效果

Effect of Huayu Xiaozheng Decoction combined with external application of Chinese herbal medicine in the treatment of ectopic pregnancy

目的探讨化瘀消癥汤配合中药外敷治疗异位妊娠的效果。方法选取2016年1月~2019年5月我院收治的82例异位妊娠保守治疗患者作为研究对象,按随机数字表法将其分为对照组和观察组,每组各41例。对照组患者给予化瘀消癥汤内服治疗,观察组患者在对照组的基础上配合消癥散外敷治疗。观察两组患者治疗后的效果和恢复情况[包块消失时间、腹痛消失时间、阴道出血消失时间以及血β-人绒毛膜促性腺激素(β-HCG)水平恢复正常的时间],比较两组患者治疗前后的孕酮(P)和β-HCG水平变化及不良反应发生情况。结果观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者的包块消失时间、腹痛消失时间、阴道出血消失时间以及血β-HCG水平恢复正常时间均短于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的P水平高于对照组,β-HCG水平低于对照组,差异有统计学意义(P<0.05);两组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论化瘀消癥汤配合中药外敷保守治疗异位妊娠的效果较好,可显著改善患者的相关血清指标水平,安全性好。

Objective To observe the effect of Huayu Xiaozheng Decoction combined with external application of Chinese herbal medicine in the treatment of ectopic pregnancy.Methods A total of 82 ectopic pregnancy patients who underwent conservative treatment in our hospital from January 2016 to May 2019 were selected as subjects.By the random number table method,they were divided into the control group and the observation group,41 cases in each group.The control group was treated with Huayu Xiaozheng Decoction in oral administration.On the basis of the control group,Xiaozheng Powder for external application was added to the observation group.The curative effect and recovery including the mass disappearance time,abdominal pain disappearance time,vaginal bleeding disappearance time,and the time returning to normal onβ-human chorionic gonadotropin(β-HCG)level after treatment were observed between the two groups.The changes of progesterone(P)andβ-HCG levels before and after treatment and the incidence of adverse reactions were compared between the two groups.Results In the observation group,the total effectiveness rate was higher than that of the control group,with statistical significance(P<0.05).In the observation group,the mass disappearance time,abdominal pain disappearance time,vaginal bleeding disappearance time,and the time returning to normal onβ-HCG level were shorter than those of the control group,the differences were statistically significant(P<0.05).After treatment,the P level in the observation group was higher than that in the control group,and theβ-HCG level was lower than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Conservative treatment of Huayu Xiaozheng Decoction combined with external application of Chinese herbal medicine in the treatment of ectopic pregnancy has a remarkable effect,which improves the level of relevant serum indicators with high safety.