阻塞性睡眠呼吸暂停低通气综合征患者严重程度与睡眠质量及白天嗜睡的相关性研究

The correlations between obstruction degree and subjective sleep quality or drowsiness in patients with obstructive sleep apnea hypopnea syndrome

目的研究阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)严重程度与睡眠质量及白天嗜睡的相关性。方法2016年5月-2018年10月在西安交通大学第二附属医院耳鼻咽喉科确诊为OSAHS的患者257例,分为轻、中、重3组,用Epworth嗜睡(Epworth sleeping scale,ESS)量表和匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)量表分别评价患者的嗜睡程度和睡眠质量,共253例患者完成量表。将呼吸睡眠暂停低通气指数(apnear-hypopnea index,AHI)与嗜睡程度、睡眠质量进行比较,评价其相关性。结果患者AHI与白天嗜睡程度呈正相关(r=0.249,P<0.001);与PSQI量表中主观睡眠质量(成分Ⅰ)呈正相关(r=0.261,P=0.004);与日间功能障碍(成分Ⅶ)呈正相关(r=0.127,P=0.025)。PSQI总体睡眠质量评分与ESS的嗜睡程度呈正相关(r=0.214,P=0.001)。结论AHI、白天嗜睡、睡眠质量三者均只能从各自角度反映OSAHS患者的严重程度。在评估OSAHS患者严重程度时,三者不能互为替代,要相互结合、综合评价。

Objective To explore the correlations between obstruction degree and subjective sleep quality or drowsiness in patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods 257 patients with OSAHS confirmed by polysomnogram(PSG)were divided into mild,moderate or severe group according to their PSG results.Before PSG,the patients were evaluated by Pittsburgh Sleep Quality Index(PSQI)and Epworth Sleeping Scale(ESS).253 patients finished the two evaluations.The correlations among ESS,PSQI and apnea hyponea index(AHI)were analyzed.Results There were positive correlations between AHI and ESS(r=0.249,P<0.001),AHI and subjective sleep quality of PSQI(r=0.261,P=0.004),AHI and day function of PSQI(r=0.127,P=0.025).Sleep quality of PSQI was positively correlated with ESS(r=0.214,P=0.001).Conclusion AHI,drowsiness and sleep quality can partly reflect the severity of OSAHS from each own angle.Their relationships are not alternative,but rather complementary with one another in the evaluation of OSAHS.