左西孟旦联合托伐普坦治疗急性心力衰竭的疗效研究

Efficacy of Levosimendan Combined With Tolvaptan in the Treatment of Acute Heart Failure

目的研究分析左西孟旦联合托伐普坦治疗急性心力衰竭的疗效。方法选取我院2016年8月-2019年1月确诊并治疗的急性心力衰竭患者102例,随机分为对照组观察组各51例。给予对照组左西孟旦治疗,观察组则在对照组的基础上联合托伐普坦进行治疗,对两组患者的心率、收缩压、射血分数及24 h尿量进行比较。结果治疗后,观察组心率、收缩压低于对照组,EF及24 h尿量高于对照组,差异有统计学意义(P<0.05);治疗后观察组心功能改善有效率明显优于对照组,差异有统计学意义(P<0.05)。结论在急性心力衰竭的临床治疗上,观察组心率、收缩压低于对照组,射血分数及24 h尿量高于对照组。

Objective To study the efficacy of levosimendan combined with tolvaptan in the treatment of acute heart failure.Methods A total of 102 patients with acute heart failure diagnosed and treated in our hospital from August 2016 to January 2019 were randomLy divided into control group observation group(51 cases).The control group was treated with levosimendan,and the observation group was treated with tolvaptan on the basis of the control group.The heart rate,systolic blood pressure,ejection fraction and 24 h urine volume were compared between the two groups.Results After treatment,the heart rate and systolic blood pressure of the observation group were lower than those of the control group,and the urine volume of EF and 24 h was higher than that of the control group.The difference was statistically significant(P<0.05).After treatment,the improvement of cardiac function in the observation group was significantly better than that of the control group.The difference was statistically significant(P<0.05).Conclusion In the clinical treatment of acute heart failure was observed in heart rate,systolic blood pressure than the control group,24 h urine volume and ejection fraction was higher.