1837例血清过敏原sIgE检测结果分析

Analysis on serum allergen-specific IgE(sIgE) in 1 837 cases

目的对血清特异性IgE(sIgE)检测结果进行分析,了解过敏性疾病或疑似过敏性疾病的就诊者过敏原sIgE检测结果特点。方法回顾性分析2017年12月-2018年11月在深圳市龙岗区第三人民医院就诊的1837例过敏性疾病或疑似过敏性疾病患者的血清过敏原sIgE检测结果。结果该院送检过敏原检测的科室主要为皮肤科、五官科和儿科,占送检例数前3位,构成比分别为68.2%(1253/1837)、22.1%(406/1837)、7.9%(145/1837);全院科室阳性检出率占据前3位的过敏原是户尘螨、树花粉和牛奶,检出率为39.0%(718/1837)、14.5%(268/1837)和13.2%(244/1837);不同性别间过敏原检出构成比比较:男性户尘螨、猫毛皮屑、牛奶(混合)sIgE检测结果阳性率均高于女性,差异有统计学意义(P<0.01);不同年龄组间具体过敏原sIgE检测结果阳性构成比有差别(P<0.01);不同季节检出构成比有差异的过敏原为鸡蛋白、牛奶(混合)、腰果、混合霉菌、树花粉(P<0.01)。结论不同性别、年龄及季节,具体过敏原sIgE阳性检出率存在差异。

Objective To retrospectively analyze the test results of serum allergen specific IgE(sIgE)so as to explore the characteristics of sIgE in patients or suspected patients with allergic diseases.Methods The test results of sIgE in 1837 patients with allergic diseases or suspected of allergic diseases who sought medical treatment in the No.3 people’s Hospital of Longgang from December 2017 to November 2018 were retrospectively analyzed.Results The top 3 departments to submit samples for allergen detection were the Department of Dermatology,Ophthalmology and Otorhinolaryngology,and Pediatrics with the constituent ratio of 68.2%(1253/1837),22.1%(406/1837)and 7.9%(145/1837),respectively;The top 3 allergens in sIgE positive detection rate were dermatophagoides pteronyssinus,tree pollen and milk with the sIgE detection rate of 39.0%(718/1837),14.5%(268/1837)and 13.2%(244/1837),respectively.As for the comparison of allergen detection between different genders,the males had the sIgE positive detection rate in dermatophagoides pteronyssinus,cat dander and milk higher than females(P<0.01).As for different age groups,the constituent ratio of sIgE positive detection rate differed in specific allergens(P<0.01).As for different seasons,the allergens with difference in constituent ratio were egg white,milk,cashews,mixed mold and tree pollen(P<0.01).Conclusion There is difference in sIgE positive detection rate among different genders,age groups and seasons.