神经内镜下经鼻蝶手术切除垂体瘤术后并发症的观察

Observation of Postoperative Complications of Neuroendoscopic Transsphenoidal Surgery for Hypophysoma

目的探讨垂体瘤患者采用神经内镜下经鼻蝶手术切除垂体瘤对其术后并发症的影响。方法选取垂体瘤患者80例为研究对象,随机数字表法分为对照组和观察组,各40例,对照组采用显微镜下经鼻蝶手术切除垂体瘤,观察组予以神经内镜下经鼻蝶手术切除垂体瘤治疗,比较2组手术相关指标及并发症情况。结果观察组术后并发症总发生率5.00%,低于对照组的22.50%;观察组手术时间及术后住院时间分别为(86.54±8.12)min及(6.13±1.21)d,短于对照组的(120.53±8.62)min及(9.14±2.13)d;观察组术中出血量(52.34±6.25)mL,少于对照组的(74.53±6.62)mL,差异均有统计学意义(P<0.05)。结论垂体瘤患者采用神经内镜下经鼻蝶手术切除垂体瘤效果较好,可降低术后并发症发生率,缩短住院时间。

Objective To explore the effect of the endoscopic transsphenoidal resection on postoperative complications in patients with hypophysoma.Methods 80 patients with hypophysoma were selected as the research objects and were randomly divided into the control group and the observation group,with40 cases in each group.The control group was treated with the transsphenoidal surgery with microscope to resect hypophysoma,while the observation group with the transsphenoidal surgery with neuroendoscope.The relevant indexes and complications of the two groups were compared.Results The total incidence of postoperative complications in the observation group(5.00%)was lower than that in the control group(22.50%).The operative time and postoperative hospital stay in the observation group[(86.54±8.12)minutes and(6.13±1.21)days]were respectively shorter than those in the control group[(120.53±8.62)minutes and(9.14±2.13)days].The intraoperative blood loss in the observation group[(52.34±6.25)mL]was less than that in the control group[(74.53±6.62)mL],with statistically significant differences(P<0.05).Conclusion It is significantly effective for patients with hypophysoma to undergo the neuroendoscopic transsphenoidal resection,which can reduce the incidence of postoperative complications and shorten the length of hospital stay.