1例疑似肺曲霉合并结核感染患者的药学监护

Pharmaceutical Care for a Patient with Suspected Pulmonary Aspergillosis Infection and Tuberculosis Infection

临床药师通对1例疑似肺曲霉合并结核感染患者开展药学监护,发现药物治疗重复及治疗矛盾,并协助医师优化治疗方案。在对患者进行药物整合过程中避免了重复用药的发生;在疾病治疗的过程中依据药物的药动学特征协助医师调整治疗方案,避免了利福平、伏立康唑、卡泊芬净之间的相互作用对疾病疗效的影响;通过对药品不良反应(ADR)的分析协助临床合理应对药物产生的药品不良反应(ADR),为患者安全用药提供了保障。

Clinical pharmacist conducted pharmaceutical monitoring for a patient with suspected pulmonary aspergillosis infection and tuberculosis infection,and found that the drug treatment was repeated and contradicted.Clinical pharmacist assisted physician in optimizing the treatment plan to avoid the occurrence of repeated medications in the drug combination.In the process of disease treatment,physician adjusted the treatment plan and avoided the influences of the interactions among rifampicin,voriconazole and caspofungin on the curative effect according to the pharmacokinetic characteristics of the drugs.The analysis of the ADRs could promote reasonable clinical responses to the ADRs induced by drugs,which provides a guarantee for the safe use of drugs.