功能磁共振成像与术后认知功能障碍

Functional magnetic resonance imaging and postoperative cognitive dysfunction

近年来,功能磁共振成像(functional magnetic resonance imaging,fMRI)在神经精神领域的发展为寻找术后认知功能障碍(postoperative cognitive dysfunction,POCD)的客观诊断指标提供了新思路。文章从理论和实际两方面,介绍当前fMRI在POCD领域的应用情况,为今后的探索与实践提供支持。文章概述了fMRI及其在神经、精神疾病中的应用;分析fMRI用于POCD的理论可行性及技术优势,列举现有研究成果,探讨实际应用中的局限性。随着技术不断改进、应用不断深入、联合研究更多开展,有理由相信,fMRI对于POCD的预测、诊断价值会在临床实践中越来越得以凸显。

In recent years,the development of functional magnetic resonance imaging(fMRI)in the field of neurology and psychiatry has provided new thoughts for determining the objective diagnostic indicators of postoperative cognitive dysfunction(POCD).This paper introduces the current application of fMRI in the field of POCD both in theory and practice,and provides supports for future exploration and practice.This paper overviews fMRI and its application in neurological and psychiatric diseases,analyzes the theoretical feasibility and technical advantages of fMRI for POCD,lists the current research achievements,and discusses the limits in practice.With the continuous improvement of technology,deepening of application and conduct of joint research,fMRI's predictive and diagnostic value for POCD will become increasingly prominent in clinical practice.