摘要
目的了解上海市嘉定区妇女孕前、孕中期和孕晚期体内维生素D(Vitamin D,VD)水平的现状,探讨孕中期和孕晚期VD水平的影响因素。方法选取2016年9月至2018年12月在上海市嘉定区妇幼保健院参加孕前检查并随访到分娩的94名妇女为研究对象,采用化学发光法检测孕前、中期和晚期血清中的VD水平,共检测282份血清。结果94名妇女的孕前、孕中期和晚期的VD缺乏率分别为:40.4%、57.4%和48.9%。混合线性模型结果显示,近1年内有过染发/烫发的妇女孕期血清VD水平较低(P<0.05),孕期经常喝牛奶和吃深海鱼的妇女在孕期VD水平较高(P<0.05)。结论上海嘉定区妇女孕前和孕期VD缺乏普遍,应该重视在孕前和孕期VD的补充。
Objective To investigate the levels of serum Vitamin D(VD)from preconception to pregnancy in Jiading district of Shanghai,and explore the risk factors of VD concentration deficiency in the second and third trimester of pregnancy.Methods A total of 94 women who planned to have antenatal care and delivery in Maternal and Child Health Hospital of Jiading district of Shanghai from September 2016 to December 2018 were recruited as the study participants.Chemiluminescent immunoassay(CLIA)was used to examine the concentration of women’s serum VD from preconception to pregnancy.A total of 282 serum samples were detected.Results The prevalence of VD deficiency among 94 women from preconception to pregnancy were 40.4%,57.4%and 48.9%respectively.Results of the mixed linear model showed that women who had dyed or permed hair within the past 1 year had significantly lower serum VD levels during pregnancy(P<0.05),and women who often drank milk and ate deep-sea fish during pregnancy had higher VD levels during pregnancy(P<0.05).Conclusions VD deficiency was common among women in Jiading district of Shanghai,and it should be emphasized to supplement VD before and during pregnancy.
作者
张玉
武常倩
马晓英
喇雪娜
张妍
毛红芳
蔡徐山
吴守乐
尹东晓
蒋泓
ZHANG Yu;WU Chang-qian;MA Xiao-ying;LA Xue-na;ZHANG Yan;MAO Hong-fang;CAI Xu-shan;WU Shou-le;YIN Dong-xiao;JIANG Hong(Department of Maternal,Child and Adolescent Healthy School of Public Healthy NHC Key Laboratory of Health Technology Assessment,Fudan University,Shanghai 200032,China;Jiading District Center for Disease Control and Prevention,Shanghai 201899,China;Maternal and Child Health Care Hospital of Jiading District,Shanghai 201812,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2020年第1期41-45,共5页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金(81973057)
上海市第四轮公共卫生三年行动计划重点学科建设资助(15GWZK0402)
上海市高峰学科建设,上海市高水平地方高校建设,上海市自然科学基金(19ZR1405900)~~
关键词
孕前
孕期
维生素D
维生素D缺乏
Preconception
Pregnant women
Vitamin D
Vitamin D deficiency