低温大气压等离子体治疗慢性创面研究进展

Advances in the research of cold atmosphere plasma in the treatment of chronic wounds

慢性创面发病机制复杂、病程长,且多发于中老年。随着人口老龄化加重,慢性创面正逐渐成为患者及医疗系统的沉重负担。近十几年来,一些学者观察到低温大气压等离子体有抗感染及促进创面愈合的作用。笔者通过广泛查阅国内外近年来关于慢性创面治疗和低温大气压等离子体的生物学作用的文献,回顾低温大气压等离子体用于慢性创面治疗的研究进展,旨在为慢性创面的治疗提供参考。

Chronic wounds are characterized by complex pathogenesis,long course of disease,and occur mostly in middle-aged and elderly people.As the population ages,chronic wounds have gradually become significant burden on the affected patients and the healthcare system.In the past decade,cold atmosphere plasma(CAP)was found to have the effects of resisting infection and promoting wound healing.By reviewing recent researches on the treatment of chronic wounds and biological effects of CAP at home and abroad,this article summarizes the research progress of CAP in the treatment of chronic wounds,aiming at providing a reference for the treatment of chronic wounds.