摘要
乳腺癌作为女性最常见的恶性肿瘤,严重威胁女性的生命健康。研究表明,多种长链非编码RNA通过靶点基因的上调或下调,在乳腺癌细胞中异常表达,进而调控乳腺癌细胞的增殖、转移、凋亡及耐药等。
Breast cancer,the most common malignant tumor in women,is a serious threat to women's health.Studies have shown that a variety of long non-coding RNAs are up-regulated or down-regulated by target genes,which are abnormally expressed in breast cancer cells,thereby regulating the proliferation,metastasis,apoptosis and drug resistance of breast cancer cells.
作者
郝杰
韩宝娟
吴雪芽
庞慧
Hao Jie;Han Baojuan;Wu Xueya;Pang Hui(Department of Oncology,Harbin Medical University Cancer Hospital,Heilongjiang Harbin 150081,China)
出处
《现代肿瘤医学》
CAS
2020年第6期1028-1031,共4页
Journal of Modern Oncology
基金
黑龙江省博士后科研启动金(编号:LBH-Q17123)
关键词
乳腺癌
长链非编码RNA
增殖
转移
凋亡
耐药
breast cancer
lncRNA
proliferation
metastasis
apoptosis
drug resistance