中性粒细胞在牙周组织炎症中的调节作用

Regulation of neutrophils in periodontal tissue inflammation

中性粒细胞是人体重要的免疫细胞之一,其在微生物杀伤、炎症和免疫调节中的作用一直广受关注。作为第一个对牙周组织感染部位作出反应的先天免疫细胞,中性粒细胞进入牙周袋成为宿主反应的一部分,以对抗微生物的挑战并维持口腔内的稳态。文章对中性粒细胞在牙周组织炎症中的调节作用做一综述。

Neutrophils are one of the important immune cells in the human body.The role of neutrophils in microbial killing,inflammation and immune regulation has been widely recognized.Neutrophils are the first innate immune cells to respond to the infection site of periodontal tissue.They enter the periodontal pocket as part of the host response to combat the microbial challenge and to maintain homeostasis in the oral cavity.In this paper,the regulation function of neutrophils in periodontal tissue inflammation is reviewed.