无创正压通气治疗重症慢性阻塞性肺疾病呼吸衰竭效果观察

Observation on the Therapeutic Effect of Non-invasive Positive Pressure Ventilation on Respiratory Failure of Severe Chronic Obstructive Pulmonary Disease

目的:观察无创正压通气治疗重症慢性阻塞性肺疾病(COPD,简称慢阻肺)呼吸衰竭的临床效果.方法:选取笔者所在医院2017年4月-2019年4月收治的153例重症COPD呼吸衰竭患者作为试验对象,经数字盲选,划分A组76例和B组77例,A组患者持续低流量吸氧,B组患者进行无创正压通气治疗,比较两组临床疗效、呼吸功能指标.结果:治疗后,B组临床治疗总有效率显著高于A组;B组氧分压(PaO2)、血氧饱和度(SaO2)明显高于A组,B组二氧化碳分压(PaCO2)低于A组.两组比较差异均有统计学意义(P<0.05).结论:在重症COPD呼吸衰竭患者中应用无创正压通气治疗,临床效果显著,患者的PaO2、SaO2、PaCO2呼吸功能指标均得到了明显改善,可临床推广.

Objective:To observe the clinical effect of noninvasive positive pressure ventilation in treating respiratory failure of severe chronic obstructive pulmonary disease(COPD).Method:A total of 153 patients with severe COPD respiratory failure admitted to our hospital from April 2017 to April 2019 were selected as experimental subjects.Through digital blind selection,76 patients in group A and 77 patients in group B,group A with continuous low-flow oxygen inhalation and group B with non-invasive positive pressure ventilation.Clinical efficacy and respiratory function indicators of the two groups were compared.Result:The total effective rate of group B was significantly higher than group A.The partial oxygen pressure(PaO2)and blood oxygen saturation(SaO2)of group B were significantly higher than those of group A,while the partial carbon dioxide pressure(PaCO2)of group B was lower than that of group A.The differences between the two groups were statistical significant(P<0.05).Conclusion:The application of non-invasive positive pressure ventilation in patients with severe COPD respiratory failure has a significant clinical effect,and the respiratory function indicators of patients PaO2,SaO2 and PaCO2 have been significantly improved,which can be clinically promoted.