CT引导下经皮微波消融术治疗结直肠癌肺转移预后的影响因素

Prognostic factors of CT-guided percutaneous microwave ablation for lung metastasis of colorectal cancer

目的探究影响结直肠癌肺转移患者CT引导下经皮微波消融术(MWA)治疗预后的高危因素。方法选取60例结直肠癌肺转移患者,均采用CT引导下MWA治疗,分析患者术后3年生存情况及影响患者预后的独立危险因素。结果 60例CT引导下MWA术后患者的中位生存期为22.00(18.204~25.796)个月。COX多因素分析显示,DFI是影响结直肠癌肺转移患者CT引导下MWA术后预后的独立保护因素,转移灶直径、数目是影响患者预后的独立危险因素(P<0.05)。结论 CT引导下经皮微波消融治疗结直肠癌肺转移患者的预后生存时间可达22个月,且预后情况与DFI、转移灶直径、转移灶数目密切相关,临床需对高危患者加以重视,尽早采取抗肿瘤干预措施。

Objective To explore the high risk factors affecting the prognosis of CT-guided percutaneous microwave ablation(MWA) in patients with lung metastases of colorectal cancer. Methods Sixty patients with lung metastasis of colorectal cancer were selected and treated with CT-guided MWA. The 3-year survival of patients and independent risk factors affecting prognosis of patients were analyzed. Results The median survival time of 60 patients with lung metastasis of colorectal cancer after CT-guided MWA was 22.00(18.204-25.796) months. The COX multivariate analysis showed that the DFI was an independent protective factor for prognosis of patients with lung metastasis of colorectal cancer after CTguided MWA, the diameter and the number of metastasis were independent risk factors for prognosis of patients(P<0.05).Conclusion The patients with lung metastasis of colorectal cancer treated by CT-guided MWA has the survival time of about 22 months, and the prognosis of patients will be deeply affected by DFI, the diameter and the number of metastasis.It is necessary to pay attention to high-risk patients and take anti-tumor interventions as early as possible in clinic.