环磷腺苷葡胺配伍丹红注射液治疗冠心病患者的效果

Effect of meglumine adenosine cyclophosphate combined with Danhong injection on patients with coronary heart disease

目的观察环磷腺苷葡胺配伍丹红注射液治疗冠心病的效果。方法选取2018年1月至2019年1月我院收治的115例冠心病患者作为研究对象,根据不同治疗方式将其分成对照组(57例)和研究组(58例)。对照组予以丹红注射液,研究组在此基础上给予环磷腺苷葡注射液治疗。比较两组患者治疗前、后的IMT、颈动脉斑块积分、心绞痛发生率和发作频度。结果治疗后,研究组IMT、颈动脉斑块积分低于对照组(P<0.05)。研究组心绞痛发生率为24.14%,低于对照组的56.14%(P<0.05);治疗后,研究组心绞痛发作次数、每次发作的持续时间均显著优于对照组(P<0.05)。结论环磷腺苷葡胺配伍丹红注射液明显改善了冠心病患者颈动脉斑块积分、IMT及心绞痛发作频度。

Objective To observe the effect of meglumine adenosine cyclophosphate combined with Danhong injection in the treatment of coronary heart disease. Methods A total of 115 patients with coronary heart disease admitted in our hospital from January 2018 to January 2019 were selected as the research objects and divided into control group(57 cases)and study group(58 cases) according to different treatment methods. The control group was treated with Danhong injection,and the study group was treated with meglumine adenosine cyclophosphate injection on this basis. IMT, carotid plaque score, incidence and frequency of angina pectoris before and after treatment were compared between the two groups.Results After treatment, IMT and carotid plaque score in the study group were lower than those in the control group(P <0.05). The incidence of angina pectoris in the study group was 24.14%, which was lower than 56.14% in the control group(P<0.05);after treatment, the number of angina pectoris attack and the duration of each attack in the study group were significantly better than those in the control group(P <0.05). Conclusion Meglumine adenosine cyclophosphate combined with Danhong injection can significantly improve carotid plaque score, IMT and the frequency of angina pectoris attacks in patients with coronary heart disease.