骨髓炎汤治疗胫骨慢性骨髓炎的临床疗效观察

Clinical Research on the Efficacy of Gusuiyan Decoction in Treating Tibia Chronic Osteomyelitis

目的:评价骨髓炎汤在胫骨慢性骨髓炎治疗中的临床疗效。方法:从2016年11月至2018年8月,共收集胫骨慢性骨髓炎病例64例,按实际治疗方案分为两组(各32例)。治疗组予以骨髓炎汤治疗,同时结合对患者的舌象、脉象等综合分析,进行中医临床辨证分型,随证加减用药。对照组予以抗生素及全身支持治疗。连续治疗6个月。采用VAS评分及SF-36量表作为疗效评价标准。结果:治疗后两组VAS评分及疗效评价明显优于治疗前,差异有统计学意义(P<0.05);治疗后两组VAS评分及治疗有效率差异无统计学意义(P>0.05);治疗组不良反应发生率低于对照组,两者差异有统计学意义(P<0.05)。结论:骨髓炎汤可有效降低VAS评分,提高SF-36量表评分。对胫骨骨髓炎疗效良好,安全性高,值得临床推广应用。

Objective:To evaluate the clinical efficacy of Gusuiyan Decoction in treating tibia chronic osteomyelitis.Methods:64 patients with the tibia chronic osteomyelitis from Nov.2016 to Aug.2018 were divided into 2 groups according to actual treatment.Patients in treatment group were treated by Gusuiyan Decoction with medicine addition and reduce on accordance with comprehensive analysis of the patient’s tongue image and pulse of the clinical syndrome differentiation of traditional Chinese medicine.while the control group were treated with antibiotic and general supports.All patients were evaluated by score of VAS and SF-36 after 6 months treatment.Results:The VAS scores and efficacy evaluations of the two groups were significantly better than those before treatment,and the difference was significant(P<0.05).There was no significant difference in VAS scores and treatment efficiency between the two groups after treatment(P>0.05).there was a significant difference between two groups,and the incidence of adverse reactions in the treatment group was lower than that in the control group(P<0.05).Conclusion:Gusuiyan Decoction could reduce VAS score and raise SF-36 score effectively.It has wonderful efficacy and high security on tibia osteomyelitis,which is worthy of clinical application.