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HAIC+索拉非尼治疗巨块型肝癌伴发Ⅲa型门静脉癌栓降期后手术切除病例报道1例

A case of massive liver cancer with type Ⅲa portal vein tumor thrombus treated with HAIC+ Sorafenib and subsequent surgical resection
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摘要 肝脏是结直肠癌最常见的首发转移器官,而肝转移灶往往又是全身化疗效果最差的病灶,因此肝转移灶治疗效果与患者的生存期密切相关。肝动脉局部灌注化疗由于肿瘤局部药物浓度高,而外周药物浓度低,因此增加局部治疗效果的同时,降低了全身毒副反应。瑞格菲尼是一个多靶点、多激酶抑制剂,其作用机制涉及到至少10个靶点,作用于肿瘤发生、发展的多个环节,作为结直肠癌三线治疗用药在临床应用中取得了较好效果。本例患者采用上述两种治疗方法相结合,取得了不错的效果,值得同行们进一步研究探讨。
作者 杨晓伟 董家鸿 曾建平 刘影 任志忠 岳元勋 童翾 张跃伟 Yang Xiao-wei;Dong Jia-hong;Zeng Jian-ping
出处 《肝癌电子杂志》 2019年第4期43-46,共4页 Electronic Journal of Liver Tumor
基金 国家自然科学基金(81571783)
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