运动对胰岛β细胞功能的影响

Effects of exercise on islet β cell function

胰岛β细胞功能障碍是糖尿病发病的重要病理基础,因此,保护胰岛β细胞功能是防止糖尿病发生的关键措施。现已明确,科学合理的运动锻炼能够改善机体的胰岛素抵抗。同样运动对受损的胰岛β细胞功能具有修复作用,同时改善糖、脂代谢,从而使糖尿病个体达到良好的代谢水平。作为简便、经济的干预方式,运动对于糖尿病的预防具有重要意义。

Islet β cell dysfunction is a hallmark characteristic of diabetes mellitus(DM)and uncovering key ways to prevent this dysfunction is critical for the prevention of DM.Evidence suggests that scientific and rational exercise regimen can improve systemic insulin resistance.Moreover,exercise regimen has been shown to preserve β cell function,potentially by improving glucose and lipid homeostasis,thereby allowing individuals with DM to achieve optimum blood glucose levels.Therefore,as a simple and economical intervention,exercise can be a great tool to prevent DM.