中医药防治大肠息肉术后复发的Meta分析

Meta-analysis of Chinese Medicine for Prevention and Treatment of Recurrence of Colorectal Polyps

目的:评价中医药防治大肠息肉术后复发的效果。方法:计算机检索2000年-2019年中国知网、维普中文科技期刊数据库、万方数据中发表的用中医防治大肠息肉术后复发的临床随机对照试验(RCT),采用RevMan5.3软件对符合纳入标准的17篇文献共1737例患者进行Meta分析。结果:比较治疗组与对照组术后1年、2年复发率,治疗组与对照组复发率差别有统计学意义(P<0.00001),敏感性分析(术后1年)提示结果较稳定,具有可靠性。结论:中医药对降低大肠息肉术后复发率有较好的效果,然纳入的高质量文献相对较少,上述结论还需要许多高质量研究加以验证。

Objective:To evaluate the effect of traditional Chinese medicine on prevention and treatment of recurrence of colorectal polyps.Methods:A computer-based randomized controlled trial (RCT) published in the Chinese Journal of China Knowledge Network,Weipu Chinese Science and Technology Journal,and Wanfang Data for the prevention and treatment of postoperative recurrence of colorectal polyps was performed by using the RevMan5.3 software.A total of 1737 patients in 17 articles underwent a meta-analysis.Results:The recurrence rate of the treatment group and the control group was 1 year and 2 years after operation.The recurrence rate of the treatment group and the control group was statistically significant (P<0.00001).The sensitivity analysis (1 year after surgery) showed that the results were stable.Has reliability.Conclusion:Traditional Chinese medicine has a good effect on reducing the recurrence rate of colorectal polyps.However,the high quality literature is relatively rare.The above conclusions need to be verified by many high quality studies.