急性胰腺炎采用奥曲肽及加贝酯的整体治疗效果分析

Overall Curative Effect Analysis of Octreotide and Gabexate on Acute Pancreatitis

目的分析急性胰腺炎采用奥曲肽及加贝酯的整体治疗效果。方法对照组采取胰腺炎基础治疗,并给予奥曲肽治疗,观察组在应用对照组治疗方案基础上加用加贝酯。对比两组临床疗效,治疗前后的IL-6、IL-8、TNF-α、CRP水平。结果研究组总有效率为92.42%,显著高于对照组的77.27%(P<0.05)。两组治疗前IL-6、IL-8、TNF-α、CRP水平无显著差异,治疗后两组上述指标与治疗前相比均改善显著,研究组各指标改善幅度更优(P<0.05)。结论急性胰腺炎采用奥曲肽及加贝酯的整体治疗效果确切,可显著遏制患者炎症反应。

Objective to analyze overall effect of octreotide and gabexate in treatment of acute pancreatitis.Methods control group was treated with basic treatment of pancreatitis and octreotide,and bservation group with gabexate on the basis of control group treatment.Compare levels of IL-6,IL-8,TNF-αand CRP before and after treatment.Results total effective rate of study group was 92.42%,significantly higher than control group(77.27%)(P<0.05).IL-6,IL-8,TNF-αand CRP levels showed no significant difference between two groups before treatment.Above indexes in two groups were significantly improved after treatment,improvement range of each index in study group was better(P<0.05).Conclusion octreotide and gabexate can achieve accurate effectin treatment of acute pancreatitis,and inhibite inflammatory response of patients significantly.