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“扶正治癌”通过免疫编辑防治肺癌的研究进展 被引量:11

“Treating cancer by cultivating Healthy Qi” through immune editing to prevent and treat lung cancer
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摘要 中医学认为肿瘤形成的主要原因为"正气"不足,提倡"养正积自消"的治则,从而针对性地选择可以提高或调节免疫功能的中药来增强机体的免疫功能,以达到抑制肿瘤的目的。免疫理论指出免疫系统不但有免疫抑制作用,防止自身免疫病;而且有免疫监视作用,预防肿瘤免疫逃逸。随着对免疫系统的深入研究,研究人员发现以一种整体性来发挥作用,这与中医学的整体观念极其相似。"扶正治癌"一方面能够有效改善癌症患者的生活质量、延长其生存期,另一方面能够调控免疫编辑,从而抑制肿瘤细胞逃避免疫监视、增强机体免疫功能从而阻止免疫逃逸预防癌症转移的发生。以下将从几方面探讨"扶正治癌"通过免疫编辑防治肺癌的研究进展:肺癌发病与免疫调控紊乱的关系、"扶正治癌"的优势、"扶正治癌"调控免疫编辑等。 Traditional Chinese medicine believes that the main cause of tumor formation is the lack of"Healthy Qi",and advocated the treatment principle of"cultivating Healthy Qi and self-elimination of pathogenic factors",so as to select the traditional Chinese medicine that can improve or regulate immune function to enhance the immune function of the body,so as to achieve tumor suppression.The theory of immunity indicates that the immune system not only has an immunosuppressive effect,but also prevents autoimmune diseases;and it has an immune surveillance function to prevent tumor immune escape.With an in-depth study of the immune system,the researchers found that it works in a holistic manner,which is very similar to the overall concept of Chinese medicine.On the one hand,"Treating cancer by cultivating Healthy Qi"can effectively improve the quality of life of cancer patients and prolong their survival.On the other hand,it can regulate immune editing to inhibit tumor cells from escaping immune surveillance and enhance immune function,thereby preventing immune escape and preventing cancer metastasis.The following will discuss the research progress of prevention and treatment of lung cancer through immune editing of"Treating cancer by cultivating Healthy Qi"from the several aspects:the relationship between the incidence of lung cancer and immune regulation disorders,the advantages of"Treating cancer by cultivating Healthy Qi",and the regulation of immune editing by"Treating cancer by cultivating Healthy Qi".
作者 陈南楠 田建辉 CHEN Nannan;TIAN Jianhui(Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China;Oncology Instiute of Traditional Chinese Medicine,Shanghai Academy of Traditional Chinese Medicine,Shanghai 200032,China)
出处 《吉林中医药》 2020年第1期128-132,共5页 Jilin Journal of Chinese Medicine
基金 国家自然科学基金项目(81373621,81774166) 上海市卫计委市级医疗卫生优秀学科带头人培养计划资助项目(2017BR044)
关键词 扶正治癌 免疫编辑 肺癌 中医 正虚 treating cancer by cultivating healthy qi immune editing lung cancer traditional Chinese medicine asthenia of healthy qi
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