摘要
Fungal infection of human nails,or onychomycosis,affects 10%of the world's adult population,but current therapies have various drawbacks.In this work,we employed a self-made low-temperature plasma(LTP)device,namely,an atmospheric-pressure plasma jet(APPJ)device to treat the nails infected with Trichophyton rubrum(T.rubrum)with the aid of persulfate solution.We found that persulfate solution had a promoting effect on plasma treatment of onychomycosis.With addition of sodium persulfate,the APPJ therapy could cure onychomycosis after several times of treatment.As such,this work has demonstrated a novel and effective approach which makes good use of LTP technique in the treatment of onychomycosis.
作者
Qunxia ZHANG
Cao FANG
Zhu CHEN
Qing HUANG
张群霞;方草;陈祝;黄青(Key Laboratory of High Magnetic Field and Ion Beam Physical Biology,Institute of Technical Biology and Agriculture Engineering,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230031,People’s Republic of China;University of Science and Technology of China,Hefei 230026,People’s Republic of China;Anhui Jianzhu University,Hefei 230601,People's Republic of China)
基金
We would like to thank Mr Chuankai Xia and Dr Chunjun Yang for providing Trichophyton rubrum
A portion of this work(ESR measurement)was performed with assistant of Dr Wei Tong on the Steady High Magnetic Field Facilities,High Magnetic Field Laboratory,CAS
This work is supported by National Natural Science Foundation of China(Nos.11635013 and 11775272).
