超声、MRI、钼靶联合检测对乳腺良恶性肿块的鉴别诊断价值

Value of ultrasound,magnetic resonance imaging and molybdenum target in differential diagnose of benign and malignant breast masses

目的研究超声、核磁共振成像(MRI)、钼靶联合检测对乳腺良恶性肿块的鉴别诊断价值。方法选择2014年6月至2019年6月汾西矿业(集团)有限责任公司职工总医院收治的100例乳腺肿块患者为研究对象,均行病理学检查。所有患者在穿刺活检或手术前15 d分别完成超声、MRI、钼靶检测。以病理学诊断结果为标准,分析3种方法联合检测对乳腺肿块良、恶性的敏感性、特异性。结果100例乳腺肿块患者通过穿刺或手术活检结果显示,乳腺恶性肿块例28例(28.00%),乳腺良性肿块72例(72.00%)。100例乳腺肿块患者经超声检测共诊断正确83例,Kappa值为0.608;MRI检测共诊断正确87例,Kappa值为0.694;数字化钼靶X线检测共诊断正确78例,Kappa值为0.488;联合检测共诊断正确99例,Kappa值为0.976。联合检测乳腺良、恶性肿块的灵敏度、特异度、准确度、预测值高于单独检测(P<0.05)。结论超声、MRI、钼靶联合检测能有效提高鉴别乳腺良、恶性肿块的准确性,为乳腺肿块病变诊断及治疗提供影像学信息。

Objective To investigate the value of ultrasound,magnetic resonance imaging(MRI)and molybdenum target in differential diagnose between benign and malignant breast masses.Methods One hundred patients with breast masses hospitalized in Staff General Hospital of Minxi Mining Group from June 2014 to June 2019 were selected as research objects.And they all underwent pathological examination.Ultrasound,MRI and molybdenum target were performed on the patients prior to operation or 15 days before puncture biopsy.The sensitivity and specificity of the three single detection methods and combined detection in differential diagnose between benign and malignant breast masses were compared,with the pathological results as standards.Results The results of puncture or surgical biopsy in 100 cases of breast masses showed 28 cases(28.00%)of malignant breast masses,and 72 cases(72.00%)of benign breast masses.Among the 100 patients,ultrasound confirmed 83 cases correctly,Kappa=0.608;MRI determined 87 cases correctly,Kappa=0.694;molybdenum target correctly confirmed 78 cases,Kappa=0.488;while a total of 99 cases were diagnosed correctly by combined detection,and the Kappa value was 0.976.The sensitivity,specificity,accuracy and predictive value of combined detection in differentiating benign and malignant breast masses were significantly higher than those of three single detection methods(P<0.05).Conclusions The combined detection of ultrasound,MRI and molybdenum target can effectively improve the accuracy of differential diagnose of benign and malignant breast masses,and provide imaging information for the diagnosis and treatment.