抗HIV抗体药物研究进展

Research progress of anti-HIV antibody drugs

HIV-1感染是危害全球公共健康的严重问题。随着抗体技术的不断进步,一些抗HIV单克隆抗体在临床试验中取得了较好的结果,第一个用于治疗HIV感染的单克隆抗体药物Ibalizumab已上市。针对HIV的双特异性和多特异性抗体的研发也取得了较大进展,但同时也面临挑战。

HIV-1 infection is a serious problem endangering global public health.With the continuous progress of antibody technology,many anti-HIV monoclonal antibodies have shown satisfying outcome in clinical trials,The first monoclonal antibody drug for HIV-infection treatment,Ibalizumab,has come onto market.In addition,the research and development of bi-specific and multi-specific antibodies against HIV has also made great progress,but also facing some challenges.