探究腹腔镜联合促性腺激素释放激素激动剂治疗子宫内膜异位症伴不孕症的效果

Investigation of the Effect of Laparoscopy Combined with Gonadotropin Releasing Hormone Agonist in the Treatment of Endometriosis with Infertility

目的探究腹腔镜联合促性腺激素释放激素激动剂治疗子宫内膜异位症伴不孕症的效果。方法选取于2018年3月-2019年1月间在南阳市第二人民医院妇二科收治的子宫内膜异位症伴不孕症患者82例为研究对象,采取随机表法将者分为对照组(41例)与观察组(41例),对照组采用腹腔镜手术治疗,观察组采用腹腔镜联合促性腺激素释放激素激动剂进行治疗,比较两组患者的临床效果、治疗前后卵巢功能以及随访妊娠率以及复发率。结果观察组的临床效果明显高于对照组;同时治疗后观察组的雌二醇(E2)的水平高于对照组,促黄体生长素(LH)以及促卵泡激素(FSH)的水平低于对照组;且观察组的妊娠率高于对照组,复发率低于对照组(P<0.05)。结论采用腹腔镜联合促性腺激素释放激素激动剂治疗子宫内膜异位症伴不孕症具有显著的临床效果,能有效改善患者的卵巢功能,同时有效提高妊娠率并降低复发率。

Objective To investigate the effect of laparoscopy combined with gonadotropin releasing hormone agonist in the treatment of Endometriosis with Infertility. Methods 82 patients with Endometriosis and Infertility from March, 2018 to January,2019 in the hospital were selected as the subjects. All the patients were randomly divided into control group(41 cases)and observation group(41 cases). The control group were treated with laparoscopic surgery, while the observation group were treated with laparoscopy combined with gonadotropin releasing hormone agonist. The clinical effect, ovarian function, pregnancy rate and recurrence rate before and after treatment were compared between the two groups. Results The clinical effect of the observation group was significantly higher than that of the control group, and the level of estrogen(E2)in the observation group was higher than that in the control group, and the levels of growth-promoting hormone(LH)and follicular hormone(FSH)in the observation group were lower than those in the control group. The pregnancy rate in the observation group was higher than that in the control group, and the recurrence rate was lower than that in the control group(P<0.05). Conclusion Laparoscopy combined with gonadotropin releasing hormone agonist has significant clinical effect in the treatment of Endometriosis with infertile women. It can effectively improve the ovarian function, increase the pregnancy rate and reduce the recurrence rate.