降钙素原与C-反应蛋白及白细胞联合检测诊断新生儿感染性肺炎的价值分析

Analysis of the Value of PCT, CRP, WBC Combined Detection in the Diagnosis of Neonatal Infectious Pneumonia

目的探讨降钙素原(PCT)、C-反应蛋白(CRP)、白细胞(WBC)联合检测对新生儿感染性肺炎的诊断价值。方法回顾性分析2018年9月-2019年3月焦作市妇幼保健院收治的70例新生儿感染性肺炎临床资料,依据感染病因分为细菌感染组(38例)和非细菌感染组(32例)。同时选取30例在焦作市妇幼保健院分娩的健康新生儿为对照组。分别对三组新生儿的PCT、CRP和WBC水平进行检测,分析检测结果。结果细菌感染组PCT、CRP、WBC水平均高于非细菌感染组和对照组,差异有统计学意义(P<0.05);细菌感染组PCT、CRP、WBC联合检测阳性率(92.11%)均高于对照组(20.00%)和非细菌感染组(56.25%),差异有统计学意义(P<0.05)。结论 PCT、CRP、WBC联合检测在新生儿感染性肺炎诊断中具有一定应用价值,对临床新生儿感染性肺炎的诊断治疗以及预后的评估具有重要意义。

Objective To evaluate the diagnostic value of combined detection of calcitonin(PCT), C-reactive protein(CRP),leukocyte(WBC) combined detection in diagnosis of neonatal infectious pneumonia. Methods The clinical data of 70 neonates with infectious pneumonia treated in the hospital from September, 2018 to March, 2019 were analyzed retrospectively. According to the cause of infection, they were divided into bacterial infection group(38 cases) and non-bacterial infection group(32 cases). At the same time, 30 healthy neonates who gave birth in the hospital were selected as the control group. The levels of PCT, CRP and WBC in the three groups were measured and the results were analyzed. Results The levels of PCT, CRP and WBC in bacterial infection group were higher than those in non-bacterial infection group and control group(P<0.05). The positive rate of PCT, CRP and WBC in bacterial infection group(92.11%) was higher than that of control group(20.00%) and non-bacterial infection group(56.25%). The difference was significant(P<0.05). Conclusion The combined detection of PCT, CRP and WBC is of great value in the diagnosis of infectious pneumonia in the newborn, and it is of great significance to the diagnosis and treatment of the infectious pneumonia in the newborn and the evaluation of the prognosis.