处方点评对抗菌药物合理应用的价值研究

Study on the Value of Prescription Evaluation on the Rational Application of Antibacterial Drugs

目的探讨处方点评对干预临床抗菌药物合理应用的价值。方法选取2017年7月-2018年6月期间河南科技大学第三附属医院门诊及住院患者用药记录为样本,对抗菌药物使用率、抗菌药物费用占比及使用强度进行对比分析。结果通过处方点评制度干预后,急诊、门诊、住院部及Ⅰ类切口抗菌药物使用率从46.21%、28.23%、69.37%、89.27%下降至33.16%、21.01%、56.42%、41.23%;抗菌药物费用占比从19.93%下降至15.13%;抗菌药物使用强度从94.16 DDD/100人/d下降至59.42 DDD/100人/d。结论处方点评制度通过对于临床抗菌药物使用的干预,降低抗菌药物使用率、抗菌药物费用占比及抗菌药物使用强度,减少患者治疗成本,同时提升医院管理及治疗水平,值得临床推广使用。

Objective To explore the value of prescription evaluation for the rational application of interventional clinical antibacterial drugs. Methods The drug records of outpatients and inpatients in the hospital from July, 2017 to June, 2018 were selected as samples. The use rate of antibiotics, the proportion of antibacterial drugs and the intensity of use were compared and analyzed.Results After intervention by the prescription review system, the use rate of antibiotics in Emergency Department, Outpatient Department, Inpatient Department and class I incision decreased from 46.21%, 28.23%, 69.37%, and 89.27% to 33.16%, 21.01%,56.42%, and 41.23%. The cost ratio decreased from 19.93% to 15.13%;the antimicrobial use intensity decreased from 94.16 DDD/100 person/d to 59.42 DDD/100 person/d. Conclusion The prescription review system reduces the use rate of antibacterial drugs,the proportion of antibacterial drugs and the intensity of antibiotics, reduces the cost of treatment for patients, and improves the management and treatment level of hospitals. It is worthy of clinical promotion.