胺碘酮联合参松养心胶囊治疗心律失常的疗效探讨

Study on the Curative Effect of Amiodarone Combined with Shensong Yangxin Capsule in the Treatment of Arrhythmia

目的探讨胺碘酮联合参松养心胶囊治疗心律失常的临床疗效。方法选取河南能源焦煤中央医院2017年2月-2018年3月期间收治的心律失常患者102例为研究对象,随机将患者分为对照组与观察组,每组各51例。对照组患者治疗药物为胺碘酮,观察组患者治疗药物为胺碘酮联合参松养心胶囊。观察两组患者的临床疗效、心律失常改善情况及不良反应发生率。结果治疗后,观察组患者的总有效率(92.16%)高于对照组(76.47%);两组患者的心输出量(Cardiac Output,CO)、心脏指数(Cardiac Index,CI)、心搏出量(Stroke Volume,SV)、射血分数(Ejection Fraction,EF)均较治疗前有所改善,但观察组的改善程度比对照组明显;且不良反应发生率(9.80%)低于对照组(25.49%,P<0.05)。结论胺碘酮联合参松养心胶囊治疗心律失常的疗效更突出,可显著改善患者的心功能及降低不良反应发生率,值得临床推广。

Objective To investigate the clinical effect of amiodarone combined with Shensong Yangxin capsule in the treatment of arrhythmia.Methods 102 patients with arrhythmia in the hospital from February,2017 to March,2018 were randomly divided into control group(n=51)and observation group(n=51).The patients in the control group were treated with amiodarone,while those in the observation group were treated with amiodarone combined with Shensong Yangxin capsule.The clinical curative effect,the improvement of arrhythmia and the incidence of adverse reactions of the two groups were observed.Results After treatment,the total effective rate of the patients in the observation group(92.16%)was higher than that in the control group(76.47%).The cardiac output(Cardiac Output,CO),cardiac index(Cardiac Index,CI),cardiac output(Stroke Volume,SV)and ejection fraction(Ejection Fraction,EF)of the two groups improved compared with those before treatment,but the improvement of the observation group was more obvious than that of the control group.The incidence of adverse reactions(9.80%)was lower than that of the control group(25.49%,P<0.05).Conclusion Amiodarone combined with Shensong Yangxin capsule is more effective in the treatment of arrhythmia,and can significantly improve the heart function of patients and the incidence of adverse reaction.So it is worthy of clinical promotion.