手术夹闭动脉瘤颈治疗颅内动脉瘤破裂的有效性和安全性

Efficacy and safety of surgical clamping of aneurysm neck in the treatment of ruptured intracranial aneurysm

目的 分析手术夹闭动脉瘤颈治疗颅内动脉瘤破裂的有效性和安全性。方法 抽取2011年5月至2019年5月于威海市中心医院治疗的颅内动脉瘤破裂患者102例,依据治疗方案将其分为两组,每组51例。对照组行介入治疗,观察组行手术夹闭动脉瘤颈治疗。比较两组相关疗效指标、功能指标,并发症。结果 对照组Rankin评分(mRS)为(1.14±0.34)分,观察组为(0.83±0.26)分,两组比较差异有统计学意义(t=5.172,P<0.05)。对照组动脉瘤复发率为23.53%(12/51),观察组为7.84%(4/51),两组比较差异有统计学意义(χ^2=4.74,P<0.05)。观察组治疗后生理职能、生理功能、情感职能评分均高于对照组(P均<0.05)。观察组脑梗死、脑水肿、脑积水、颅内出血等并发症发生率低于对照组(P<0.05)。结论 手术夹闭动脉瘤颈可有效治疗颅内动脉瘤破裂,并发症少,复发率较低。

Objective To analyze the efficacy and safety of surgically clipped aneurysm neck for the treatment of intracranial aneurysm rupture.Methods A total of 102 patients with intracranial aneurysm rupture treated in Weihai Central Hospital from May 2011 to May 2019 were selected.According to the treatment plan,they were divided into two groups,with 51 cases in each group.The control group underwent interventional therapy,and the observation group underwent surgical clamping of the aneurysm neck.The related efficacy indicators,functional indicators and complications were compared between the two groups.Results The modidied Rankin scale score of the control group was 1.14±0.34,and that of the observation group was 0.83±0.26.The difference between the two groups was statistically significant(t=5.172,P<0.05).The recurrence rate of aneurysm in the control group was 23.53%(12/51),and that in the observation group was 7.84%(4/51).The difference between the two groups was statistically significant(χ^2=4.74,P<0.05).The scores of physiological function,physiological function and emotional function of the observation group were higher than those of the control group(P<0.05).The incidence of complications such as cerebral infarction,cerebral edema,hydrocephalus and intracranial hemorrhage in the observation group was lower than that in the control group(P<0.05).Conclusions Surgical clipping of the aneurysm neck can effectively treat the rupture of intracranial aneurysms with fewer complications and lower recurrence rate.