乳酸清除率联合脑钠肽在指导急性重度心力衰竭患者救治中的临床价值观察

Clinical value observation of lactate clearance rate combined with brain natriuretic peptide(BNP)in guiding the treatment of patients with acute severe heart failure

目的:分析在急性重度心力衰竭患者临床救治中通过监测乳酸清除率及脑钠肽(BNP)指标对于患者的治疗价值。方法:2017年1月-2019年2月收治急性重度心力衰竭患者67例,随机分为两组。观察组治疗期间根据血清乳酸清除率及BNP的变化情况对治疗方案进行指导,对照组患者仅对其进行BNP监测。结果:观察组患者ICU住院时间、机械通气时间均短于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。观察组患者30 d内的再入院率和死亡率低于对照组,差异均有统计学意义(P<0.05)。结论:在急性重度心力衰竭患者临床救治过程中通过联合监测血清乳酸清除率及BNP有利于提高患者的救治效果。

Objective:To analyze the therapeutic value of monitoring lactate clearance rate and brain natriuretic peptide index in the clinical treatment of patients with acute severe heart failure.Methods:67 patients with acute severe heart failure were selected from January 2017 to February 2019,they were randomly divided into the two groups.In the observation group,the treatment plan was guided according to the changes of serum lactate and BNP,while BNP was only monitored in the control group.Results:The length of stay in ICU in the observation group the duration of mechanical ventilation was shorter than that of the control group,LVEF was higher than that of the control group,the re-entry rate and mortality rate of patients in the observation group within 30 days were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:In the course of clinical treatment of patients with acute severe heart failure,the combined monitoring of serum lactate clearance rate and BNP is conducive to improving the treatment effect of patients.