基于共词分析的我国血管生成研究领域热点分析

Analysis of hot points of angiogenesis research in China based on co-word analysis

目的对血管生成领域相关文献关键词进行共词分析,探索该领域研究热点。方法选取CNKI学术期刊中的“EI来源期刊”“核心期刊”“CSSCI”或“CSCD”作为数据来源,限定领域类型为“医药卫生科技”,以“血管生成”为检索关键词,检索类型为“主题”,检索时间为1992年~2019年6月,检索得到血管生成领域相关文献,采用pajek和SPSS 22.0等软件进行文献计量分析,统计高频词并构建共词矩阵,根据共词矩阵进行聚类分析并生成共词网络图。结果根据检索公式共得到血管生成领域核心期刊论文共2586篇,共词网络图显示关键词主要集中在干预方式、研究模型/技术、机制、评价指标及临床疾病5个主要方面。结论我国血管生成的研究热点方面中,抑制血管生成主要方向是对肿瘤的研究;促进血管生成主要方向是对子宫内膜异位症、心肌缺血等疾病的研究;实验动物主要是鸡胚尿囊膜,为相关临床和科研工作提供参考依据。

Objective To co-word analyze the key words of related literature on angiogenesis,and explore the research hotspots.Methods The data sources were“EI journals”“core journals”“CSSCI”or“CSCD”in CNKI academic journals,the field was limited as“medical,health science and technology”,with“angiogenesis”as the key word and“subject”as the search type,and the search time was from 1992 to June 2019.Pajek and SPSS 22.0 were used for literature metrological analysis.Results of co-word analysis was obtained by high frequency word statistics,keywords cluster analysis based on co-word matrix,and network graph.Results A total of 2586 research papers were obtained.The co-word network graph showed that five main aspects exist:intervention mode,research model/technology,mechanism,evaluation index and disease.Conclusion Among these hotspots on angiogenesis in China,the main direction of inhibiting angiogenesis is tumor.The main direction of promoting angiogenesis is endometriosis,myocardial ischemia and others.The main experimental animal is chick embryo allantoic membrane.These provide references for relevant clinical and research.