肝窦内皮细胞相关文献的可视化分析

Visualization analysis of literature related tosinusoidal endothelial cells

目的通过对相关文献的可视化分析,探索近47年关于肝窦内皮细胞的主要研究方向及热点。方法运用顺查法检索WOS中的SCI-E中1972年1月~2018年12月相关文献,关键词:"hapatic sinusoidal endothelial cell"OR"liver sinusoidal endothelial cell"OR"HSEC"OR"LSEC",索引:SCI-EXPANDED。以纯文本的格式导出检索结果的全记录与引用的参考文献。应用CiteSpace5.4.R3对作者、机构、关键词共现等进行可视化分析。结果共获得3474篇相关文献,2018年达到近47年的引文峰值。最高产的机构为悉尼大学,发文量最高的作者为Smedsrod B。被引频次最高的期刊是HEPATOLOGY。热点关键词为肝窦内皮细胞、储脂细胞、肝脏再生等,可形成9个聚类群。结论应用CiteSpace分析肝窦内皮细胞相关文献,展示出了目前合作的国家和机构,揭示了研究的热点,为后续研究提供了参考,对肝窦内皮细胞的研究具有重要意义。

Objective Through visual analysis of related literature,the main research directions and hot spots of sinusoidal endothelial cells in recent 47 years were explored.Methods The forward search method was used to search the relevant literature of SCI-E in WOS from January 1972 to December 2018,the key words were "hapatic sinusoidal endothelial cell" or "liver sinusoidal endothelial cell" or "HSEC" or "LSEC".index:SCI-EXPANDED.The full records and references of search results were exported in plain text format.The co-occurrence of authors,organizations and keywords were analyzed by using CiteSpace 5.4.R3.Results A total of 3474 related literatures were obtained,reaching the peak of citations in nearly 47 years in 2018.The most productive institution was the University of Sydney,and the most prolific author was Smedsrod B.The most cited journal was HEPATOLOGY.The hot key words were sinusoidal endothelial cells,lipid storage cells,liver regeneration,etc.,which could form 9 clusters.Conclusion CiteSpace is used to analyze the literature related to sinusoidal endothelial cells,showing the current cooperation countries and institutions,revealing the research hotspot,providing a reference for the follow-up research,which is of great significance for the research of sinusoidal endothelial cells.