早期糖尿病肾病中医病机探讨

Discussion on the pathogenesis of early diabetic nephropathy

辨证论治是中医药治疗早期糖尿病肾病(Diabetic Nephropathy,DN)的独特优势。病机是疾病变化发展的机理,是对疾病本质的高度概括。中医辨证论治的核心是对疾病病机不断的深化认识。深入剖析早期DN中医病机有利于提高中医药治疗本病的疗效。本文从古代文献及现代研究并结合糖尿病肾病发生发展过程,探讨早期糖尿病肾病的病机演变,认为气阴两虚为本,湿热、瘀血互结为标,涉及脏腑包括肺、脾(胃)、肾、肝,其中以脾肾亏虚为主。

Syndrome differentiation is a unique advantage of TCM on treating early DN.The pathogenesis is the mechanism of disease change and development and a high-level summary of the disease nature.The core of TCM syndrome differentiation is the continuous deepening of the disease pathogenesis.A depth analysis of early DN of TCM pathogenesis can improve the efficacy of TCM.The pathogenesis of early diabetic nephropathy was explored from ancient literature and modern research combined with the development of diabetic nephropathy.In pathogenesis of DN,Qinyin Liangxu(气阴两虚)is root cause,and Shire(湿热),Yuxue Hujie(瘀血互结)are secondary cause,including lung and spleen(stomach),kidney,liver,mainly Pishen Kuixu(脾肾亏虚).