绝经后骨质疏松症新药——罗莫索单克隆抗体综述

Review of monoclonal antibodies Romosozumab, a new drug for postmenopausal osteoporosis

骨质疏松是一种代谢性骨质病变,好发于绝经后妇女,常表现为骨骼疼痛等,可增加老年女性的骨折风险。本文基于临床常用的骨质疏松治疗药物,结合国内外研究进展,围绕新型治疗药物——罗莫索单克隆抗体的作用机制、临床应用以及药效对比等进行综述,为绝经后患有骨质疏松的妇女提供治疗选择。

Osteoporosis is a kind of metabolic osteopathy, which occurs frequently in postmenopausal women and often presents with bone pain, which can increase the risk of fracture in elderly women. Based on the commonly used clinical osteoporosis treatment drugs, combined with the research progress at home and abroad, this paper reviews the mechanism, clinical application and efficacy comparison of the new treatment drugs-romoso monoclonal antibody, so as to provide treatment options for postmenopausal women with osteoporosis.