18F-fluciclovine应用于前列腺癌诊断的进展

Progress in applications of 18F-fluciclovine in diagnosis of prostate cancer

前列腺癌是发达国家男性发病率最高的恶性肿瘤,近年来发病率在我国也呈逐年上升趋势。随着诊疗技术的发展,PET/CT检查在诊断前列腺癌中的应用日益增加。为了更加安全、有效地达到精准检测前列腺癌的目的,新型的前列腺癌PET/CT检查靶向示踪剂应运而生,18F-fluciclovine便是其中之一。18F-fluciclovine具有摄取快、显影快、代谢快的特点,对前列腺癌的复发、转移具有良好的诊断率,但是目前该方面的研究还相对较少,在其安全性、诊断效能、应用价值等方面,仍需要深入的研究。

Prostate cancer is the most common malignancy tumor among men in developed countries.The incidence rate in recent years is also increasing in China. With the development of technology, the application of PET/CT examination has been augmented in the diagnosis of prostate cancer. In order to detect prostate cancer more safely and effectively, new types of targeted tracer for PET/CT has been developed, including 18F-fluiclovine.18F-fluiclovine has the characteristics of fast uptake, rapid development and fast metabolism, which has a good diagnostic rate for the recurrence and metastasis of prostate cancer. However, at present,there are few researches and its security, diagnosis efficiency, and application value still need further research to verify.