炎症性肠病的血常规特点及其意义

Blood routine characteristics of inflammatory bowel disease and its significance

目的探讨炎症性肠病的血常规特点及其意义。方法选取2018年2月~2019年4月我院收治的50例炎症性肠病患者作为观察组,另选取同期的50例非炎症性肠病患者作为对照组,比较两组患者的血小板计数(PLT)、平均血小板体积(MPV)、血红蛋白浓度(HGB)、平均血细胞比容(MCV)、红细胞血红蛋白浓度(MCHC)、C反应蛋白(CRP)、红细胞分布宽度(RDW)和红细胞沉降率等血常规检验指标水平。结果观察组患者的PLT、RDW、CRP、红细胞沉降率均高于对照组,MPV、HGB、MCV、MCHC低于对照组,差异有统计学意义(P<0.05)。观察组中,缓解期患者的PLT、RDW、CRP、红细胞沉降率低于轻度、中度与重度患者,差异有统计学意义(P<0.05);缓解期患者的MPV、HGB、MCV、MCHC高于轻度、中度与重度患者,差异有统计学意义(P<0.05);轻度患者的PLT、RDW、CRP、红细胞沉降率低于中度与重度患者,HGB高于中度与重度患者,差异均有统计学意义(P<0.05);中度患者的PLT、RDW、CRP、红细胞沉降率低于重度患者,HGB高于重度患者,差异均有统计学意义(P<0.05)。结论在炎症性肠病患者的诊断过程中采取血常规检验,不但可以明确疾病的诊断,还有助于判断疾病的严重程度,对疾病的治疗具有较高的参考价值。

Objective To investigate the blood routine characteristics of inflammatory bowel disease and its significance.Methods From February 2018 to April 2019,50 patients with inflammatory bowel disease treated in our hospital were selected as the observation group,and 50 patients with non-inflammatory bowel disease in the same period were selected as the control group.The routine blood test indexes such as blood platelet count(PLT),mean platelet volume(MPV),concentration of hemoglobin(HGB),average red blood cell volume(MCV),red blood cell hemoglobin concentration(MCHC),C-reactive protein(CRP),red blood cell distribution width(RDW)and erythrocyte sedimentation rate of the two groups were compared.Results The PLT,RDW,CRP and erythrocyte sedimentation rate in the observation group were higher than those in the control group,and MPV,HGB,MCV and MCHC were lower than those in the control group,with statistically significant differences(P<0.05).In the observation group,PLT,RDW,CRP and erythrocyte sedimentation rate of patients in remission were lower than those of patients with mild,moderate and severe symptoms,with statistically significant differences(P<0.05).The MPV,HGB,MCV and MCHC of patients in remission were higher than those of patients with mild,moderate and severe diseases,with statistically significant differences(P<0.05).The PLT,RDW,CRP and erythrocyte sedimentation rate of patients in mild symptoms were lower than those of patients with moderate and severe symptoms,the HGB was higher than that of patients with moderate and severe symptoms,with statistically significant differences(P<0.05).The PLT,RDW,CRP and erythrocyte sedimentation rate of patients in moderate symptoms were lower than those of patients with severe symptoms,the HGB was higher than that of patients with severe symptoms,with statistically significant differences(P<0.05).Conclusion Routine blood test in the diagnosis process of inflammatory bowel disease can not only clarify the diagnosis of the disease,but also help to determine the severity of the disease,which has a high reference value for the treatment of the disease.