残胃癌的诊治研究进展

Research progress in diagnosis and treatment of gastric stump cancer

残胃癌(GSC)是指胃良性疾病行胃切除术后5年以上或胃癌行胃切除术后10年以上,残胃出现的新发癌。由于早期GSC患者临床表现不典型,就诊时多数已进展,加之本病的特殊性,导致其预后较差。GSC的发生率呈逐年上升的趋势,为探讨近年来GSC诊治的若干问题,笔者复习国内外相关文献,就其的病因、临床表现、治疗手段、预后及预防等研究进展作一综述,并提出首次胃切除手术后的随访尤为重要,早期发现、诊断及早期治疗是提高患者的生存率、改善生活质量关键。

Gastric stump cancer(GSC)refers to a primary carcinoma arising from the gastric remnant more than 5 years after surgery for benign ulcer disease or more than 10 years after surgery for gastric cancer.Because of the atypical clinical presentations of the GSC patients at the early stage,most of them are found in advanced stage when seeking for treatment,which plus the particularity of this condition,result in a poor prognosis.The incidence of GSC has shown an increasing tendency over the years.For discussion of several issues concerning the diagnosis and treatment of GSC in recent years,the authors based on review of the relevant literature at home and abroad,address its pathogenesis,clinical manifestations,treatment methods,prognosis and prevention,and also propose that the postoperative follow-up after the first gastrectomy is particularly important,and early detection,early diagnosis and early treatment are essential for improving the survival rates and the quality of life of the patients.