原发性干燥综合征腮腺及颌下腺超声表现的对比研究

Comparison of ultrasonographic findings between parotid glands and submandibular glands in primary Sjögren′s syndrome

收集2014年8月至2018年9月东南大学医学院附属江阴医院收住入院的原发性干燥综合征(pSS)患者共87例。对比分析患者双侧腮腺及颌下腺的超声图像,采用0~4分评分法,为每个腺体行半定量评分,≥2分为阳性。结果显示,87例pSS患者中,颌下腺及腮腺(均左右各一)的超声阳性率分别为94.3%(164/174)、71.3%(124/174),差异具有统计学意义(χ^2=32.22,P<0.05);颌下腺的超声评分高于腮腺,中位数分别为3分、2分(Z=9.70,P<0.05);同一涎腺的左右侧超声评分差异均无统计学意义(P>0.05)。pSS患者颌下腺的超声阳性率及超声评分均高于腮腺,提示pSS患者颌下腺较腮腺更易累及,且同一时期颌下腺的受损程度较腮腺严重。

A total of 87 patients with primary Sjögren′s syndrome(pSS)admitted in Jiangyin Hospital affiliated to South-East University Medical College from August 2014 to September 2018 were enrolled.According to severity,the ultrasonographic images of salivary glands were analyzed and graded to 0-4 scores,it is defined as positive if the scores≥2.The ultrasonographic positive rate of submandibular glands and parotid glands were 94.3%(164/174)and 71.3%(124/174),respectively(χ^2=32.22,P<0.05).The median scores of submandibular glands and parotid glands were 3 and 2(Z=9.70,P<0.05).No significant difference was found in the ultrasonographic scores between the right and left glands of the same salivary glands(P>0.05).The result indicates that the damage of submandibular glands is more severe than that of parotid glands in patients with pSS.