儿童肾病综合征和特应性疾病

Nephrotic syndrome and atopic diseases in children

肾病综合征是儿童期常见的肾小球疾病,易复发。近年来随着对其研究的深入发现,肾病综合征患儿常伴有特应性表现,其与特应性疾病呈现高共病特点。本文将从发病机制、细胞因子改变、治疗三方面探讨儿童肾病综合征和特应性疾病的关系,以期发现儿童肾病综合征和特应性疾病的相似之处,为儿童肾病综合征的治疗提供新的线索和方法。

Nephrotic syndrome is a common glomerular disease in childhood and easy to recur.It has been found that children with nephrotic syndrome are often accompanied by atopic manifestations and there is high co-morbidity between nephrotic syndrome and atopic diseases.This article reviewed the pathogenesis,cytokines and treatment of nephrotic syndrome and atopic diseases in children to explore the similarity between them to provide new clues and methods for the treatment of nephrotic syndrome in children.