富血小板血浆（PRP）联合中药治疗膝骨性关节炎的临床研究

Clinical research of traditional Chinese medicine with PRP on knee osteoarthritis

目的观察肝肾不足型膝骨关节炎采用富血小板血浆(PRP)联合中药治疗的临床疗效及安全性。方法选取2018年3月-2019年1月期间我院收治的中医辨证分型为肝肾不足型膝骨关节炎患者60例,平均分为试验组、对照组与空白组,3组均采用PRP注入膝关节关节腔内治疗。观察组联合中药口服,对照组联合口服硫酸氨基葡萄糖,空白组不采用其他方法,观察3组疗效。结果试验组总有效率为95%,总优良率85%;对照组总有效率为85%,总优良率80%;空白组总有效率为65%,总优良率45%,试验组及对照组均优于空白组,差异有统计学意义(P<0.05)。结论肝肾不足型膝骨关节炎患者采用PRP治疗有效,同时在治疗过程中联合中药或者硫酸氨基葡萄糖口服治疗,可以获得更好的效果。

Objective To observe the clinical curative effect about knee osteoarthritis of the liver and kidney deficiency type with platelet rich plasma(PRP)and combined therapy with traditional Chinese medicine(TCM).Methods During March 2018 to January 2019 of traditional Chinese medicine for liver and kidney deficiency type 60 patients with knee osteoarthritis,average divided into experimental group and control group and the blank group,three groups all use platelet rich plasma(PRP)injection of knee joint cavity treatment.Observation in combination with oral medicine,control combined oral glucosamine sulfate oral,blank group did not use other methods,three groups were treated after 3 course of treatment.Results The total effective rate of the experimental group was 95%,the the total excellent and good rate was 85%,the total effective rate of control group was 85%,the total excellent and good rate was80%,the total effective rate of blank group was 65%,the total excellent and good rate was 45%.Experimental group total effective rate with the total and total crop with no statistically significant difference were observed in the control group(P>0.05).Conclusion Liver and kidney deficiency type patients with knee osteoarthritis,the use of platelet rich plasma(PRP)is an effective method,at the same time in the treatment of combined traditional Chinese medicine(TCM)or in the process of glucosamine sulfate oral treatment,can obtain better effect.