小花清风藤中黄酮类成分的研究

Flavonoids from Sabia parviflora

目的研究小花清风藤中黄酮类成分。方法小花清风藤甲醇提取物采用D101、硅胶、制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到7个黄酮类化合物,分别鉴定为槲皮素-3-O-龙胆双糖苷(1)、camellianoside(2)、芦丁(3)、tsubakioside A(4)、山柰酚-3-O-芸香糖苷(5)、异鼠李素-3-O-芸香糖苷(6)、山柰酚(7)。结论化合物1~2、4~6为首次从清风藤属中分离得到,且为首次从该植物中分离得到。

AIM To study the flavonoids from Sabia parviflora Wall.ex.Roxb..METHODS The methanol extract of S. parviflora was isolated and purified by D101,silica and preparative HPLC column,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Seven flavonoids were isolated and identified as quercetin-3-O-gentiobioside(1), camellianoside(2), rutin(3), tsubakiosideA(4), kaempferol-3-O-rutinoside(5), isobariclisin-3-O-rutinoside(6), kaempferol(7).CONCLUSION Compounds 1-2, 4-6 are isolated from genus Sabia for the first time,which are first isolated from this plant.