正念疗法对膀胱癌行灌注化疗患者自我负担、希望、睡眠的影响

Effects of mindfulness therapy on self-burden,hope and sleep in patients undergoing perfusion chemotherapy for bladder cancer

目的 探讨正念疗法对中年膀胱癌保留膀胱行灌注化疗患者自我负担、希望、睡眠不良的影响。方法 选取2018年1月至2019年12月天津医科大学总医院收治的60例膀胱癌保留膀胱行灌注化疗患者为研究对象,依次按照化疗时间先后顺序进行编码排序分为对照组和干预组,每组30例。2组患者均泌尿外科常规护理及常规康复训练,干预组在此基础上增加正念疗法6周。于干预前和干预6周末采用自我负担感受量表(SPBS)、Herth希望量表(HHI)、失眠严重指数量表(lSI)比较2组患者治疗前后的睡眠状况及精神状况。结果 2组患者SPBS、HHI、ISI得分干预前比较差异无统计学意义(P>0.05)。干预6周后干预组患者SPBS、HHI、ISI评分分别为(47.00±1.41)、(32.61±1.94)、(19.17±1.72)分,对照组分别为(49.50±0.62)、(27.22±2.67)、(20.67±2.24)分,2组比较差异有统计学意义(t值为6.454、-7.042、2.097,P<0.01或0.05)。结论 正念疗法能有效改善膀胱癌保留膀胱行灌注患者的失眠状况以及精神状况。

Objective To explore the effect of mindfulness therapy on self burden,hope and sleep of middle-aged bladder cancer patients undergoing bladder sparing chemotherapy.Methods Sixty patients with bladder cancer treated by intravesical instillation chemotherapy with bladder preservation from January 2018 to December 2019 were selected as the study subjects.They were divided into control group and intervention group according to the sequence of chemotherapy time,with 30 cases in each group.Both groups received routine nursing and rehabilitation training in urology,and mindfulness therapy was added to the intervention group for 6 weeks.Before and 6 weeks after the intervention,the sleeping and mental status of the two groups were compared by the Self-Burden Feeling Scale(SPBS),Herth Hope Scale(HHI)and Insomnia Severity Index Scale(lSI).Results There was no significant difference in SPBS,HHI and ISI scores between the two groups before intervention(P>0.05).After 6 weeks of intervention,SPBS score of patients in the intervention group was 47.00±1.41,and that of the control group was 49.50±0.62.After 6 weeks of intervention,the total score of HHI was 32.61±1.94 in the intervention group and 27.22±2.67 in the control group.After 6 weeks of intervention,ISI score of patients in the intervention group was 19.17±1.72,and that of the control group was 20.67±2.24.The difference between the two groups was statistically significant(t values were 6.454,-7.042,2.097,P<0.01 or 0.05).Conclusions Mindfulness therapy can effectively improve insomnia and cancer emotional problems in patients with bladder cancer who underwent bladder preservation and perfusion.