摘要
目的探讨儿童Epstein-Barr(EB)病毒合并肺炎支原体(MP)感染的临床特点。方法选取EB病毒合并MP感染的87例患儿为观察组,同期治疗的单纯MP感染的70例患儿为对照组。比较两组一般资料、实验室结果及临床情况等方面的差异。结果MP合并EB病毒感染以学龄前儿童居多,MP和EB病毒合并感染患儿的白细胞较单纯MP感染略升高,天冬氨酸转氨酶(AST)、丙氨酸氨基转移酶(ALT)、磷酸肌酸激酶同工酶(CK-MB)有一过性升高;合并感染儿童的肺实质性病变程度更高,更易出现胸腔积液。合并感染的患儿临床特征表现为淋巴结易肿大,发热持续时间延长。结论与单纯肺炎支原体感染相比,儿童EB病毒合并MP感染的患儿临床表现更加严重,常累及多个器官。
Objective To investigate the clinical characteristics and influencing factors of mycoplasma pneumoniae(MP)infection with Epstein-Barr(EB)virus in children.Methods The research subjects of this experiment included 87 cases of hospitalized children with EB virus complicated with MP infection as observation group.And 70 patients with simple MP infection at the same time were selected as control group.The differences in general data,laboratory results and clinical conditions between two groups were compared and analyzed.Results EB virus combined with MP infection was mostly seen in preschool children and the gender difference was not obvious.Blood routine examination showed that white blood cells of children with MP and EB virus infection were significantly higher than thoseof children with MP infection alone(P<0.05).Serum biochemistry showed transient elevation of AST,ALT and CKMB.Imageological examination suggested that the degree of pulmonary substantive lesion was higher in children with concurrent infection and pleural effusion was more likely to happen.The clinical features of children with concurrent infection showed that lymph nodes were more prone to swelling,and the extension of fever duration.Conclusion Compared with MP infection alone,the clinical manifestation of EB virus combined with MP infection is more serious and often involves multiple organs.
作者
翟谨
徐俊
何萍
花盛浩
丰涛
Zhai Jin;Xu Jun;He Ping;Hua Shenghao;Feng Tao(Department of Clinical Laboratory,Children's Hospital affiliated to Suzhou University,Suzhou 215006,China;Dongting Community Health Service Center,Xishan District of Wuxi,Wuxi 214000,China)
出处
《临床荟萃》
CAS
2020年第2期174-176,共3页
Clinical Focus
基金
苏州市青年科技项目——Stathmin调控骨肉瘤细胞侵袭转移的功能与分子机制研究(KJXW2017024)
关键词
肺炎支原体
EB病毒
儿童
影响因素
mycoplasma pneumoniae
epstein-barr virus
child
influencing factor